Results 21 to 30 of about 21,830 (200)

Single-Entity Detection With TEM-Fabricated Nanopores

open access: yesFrontiers in Chemistry, 2021
Nanopore-based single-entity detection shows immense potential in sensing and sequencing technologies. Solid-state nanopores permit unprecedented detail while preserving mechanical robustness, reusability, adjustable pore size, and stability in different
Hongcheng Yang, Muhammad Saqib, Rui Hao
doaj   +1 more source

Membrane-Suspended Nanopores in Microchip Arrays for Stochastic Transport Recording and Sensing

open access: yesFrontiers in Nanotechnology, 2021
The transport of nutrients, xenobiotics, and signaling molecules across biological membranes is essential for life. As gatekeepers of cells, membrane proteins and nanopores are key targets in pharmaceutical research and industry. Multiple techniques help
Tim Diederichs, Robert Tampé
doaj   +1 more source

Noise in solid-state nanopores [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
We study ionic current fluctuations in solid-state nanopores over a wide frequency range and present a complete description of the noise characteristics. At low frequencies ( f ≲ 100 Hz) we observe 1/ f -type of noise.
R M M, Smeets   +3 more
openaire   +2 more sources

Lifetime of glass nanopores in a PDMS chip for single-molecule sensing

open access: yesiScience, 2022
Summary: Nanopore sensing is an emerging technology that has many biosensing applications ranging from DNA sequencing using biological pores to biomolecular analysis using solid-state pores.
Mohammed F. Alawami   +5 more
doaj   +1 more source

Concentration Polarization of High Concentration Solution in Sub-nm Nanopore [PDF]

open access: yesE3S Web of Conferences, 2021
The behavior of ion transport through the sub-nm nanopores on the film is is different from the behavior of bulk behavior. Many intriguing phenomena in ionic transport are the key to the design and fabrication of solid-state nanofluidic devices. However,
Ji Anping, Chen Yunfei
doaj   +1 more source

Ribosome Fingerprinting with a Solid-State Nanopore [PDF]

open access: yesACS Sensors, 2020
AbstractNanopores hold great potential for the analysis of complex biological molecules at the single entity level. One particularly interesting macromolecular machine is the ribosome, responsible for translating mRNA into proteins. In this study, we use a solid-state nanopore to fingerprint 80S ribosomes and polysomes from a human neuronal cell line ...
Mukhil Raveendran   +4 more
openaire   +2 more sources

Gating Protein Transport in Solid State Nanopores by Single Molecule Recognition [PDF]

open access: yesACS Central Science, 2018
Gustav Emilsson   +6 more
doaj   +2 more sources

Solid-state nanopore hydrodynamics and transport [PDF]

open access: yesBiomicrofluidics, 2019
The resistive pulse method based on measuring the ion current trace as a biomolecule passing through a nanopore has become an important tool in biotechnology for characterizing molecules. A detailed physical understanding of the translocation process is essential if one is to extract the relevant molecular properties from the current signal.
Sandip Ghosal   +2 more
openaire   +2 more sources

Integration of Solid-State Nanopores in Microfluidic Networks via Transfer Printing of Suspended Membranes [PDF]

open access: yes, 2012
Solid-state nanopores have emerged as versatile single-molecule sensors for applications including DNA sequencing, protein unfolding, micro-RNA detection, label-free detection of single nucleotide polymorphisms, and mapping of DNA-binding proteins ...
Aguilar, Carlos A.   +3 more
core   +1 more source

Solid-state nanopore sensors

open access: yesNature Reviews Materials, 2020
Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare.
Liang Xue   +5 more
openaire   +3 more sources

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