Results 1 to 10 of about 20,246 (268)

Solid-State Nanopore [PDF]

Nanoscale Research Letters, 2018
Solid-state nanopore has captured the attention of many researchers due to its characteristic of nanoscale. Now, different fabrication methods have been reported, which can be summarized into two broad categories: “top-down” etching technology and ...
Zhishan Yuan, Chengyong Wang, Xin Yi, Zhonghua Ni, Yunfei Chen, Tie Li   +5 more
doaj   +5 more sources

Aggregation and Oligomerization Characterization of ß-Lactoglobulin Protein Using a Solid-State Nanopore Sensor [PDF]

Sensors, 2023
Protein aggregation is linked to many chronic and devastating neurodegenerative human diseases and is strongly associated with aging. This work demonstrates that protein aggregation and oligomerization can be evaluated by a solid-state nanopore method at
Mitu C. Acharjee, Brad Ledden, Brian Thomas, Xianglan He, Troy Messina, Jason Giurleo, David Talaga, Jiali Li   +7 more
doaj   +2 more sources

Microfluidic Systems Applied in Solid-State Nanopore Sensors [PDF]

Micromachines, 2020
Microfluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study.
Jiye Fu, Linlin Wu, Yi Qiao, Jing Tu, Zuhong Lu   +4 more
doaj   +2 more sources

Controllable Shrinking Fabrication of Solid-State Nanopores

Micromachines, 2022
Nanopores have attracted widespread attention in DNA sequencing and protein or biomarker detection, owning to the single-molecule-scale detection accuracy.
Xin Lei, Jiayan Zhang, Hao Hong, Zhishan Yuan, Zewen Liu   +4 more
doaj   +5 more sources

Tri‐Layer Solid‐State Nanopore Arrays with Crosstalk Suppression for High‐Throughput, Femtomolar‐Level Biosensing [PDF]

Advanced Science
Solid‐state nanopore arrays are emerging as powerful tools for label‐free, ultrasensitive biosensing, yet their implementation has been constrained by inter‐pore crosstalk and limited fabrication uniformity.
Silu Feng, Qinglong Luo, Siqi Ai, Suiwei Shen, Chengyong Wang, Zhishan Yuan   +5 more
doaj   +2 more sources

Controlling DNA Translocation Through Solid-state Nanopores [PDF]

Nanoscale Research Letters, 2020
Compared with the status of bio-nanopores, there are still several challenges that need to be overcome before solid-state nanopores can be applied in commercial DNA sequencing. Low spatial and low temporal resolution are the two major challenges.
Zhishan Yuan, Youming Liu, Min Dai, Xin Yi, Chengyong Wang   +4 more
doaj   +3 more sources

Ribosome Fingerprinting with a Solid-State Nanopore. [PDF]

ACS Sens, 2020
AbstractNanopores hold great potential for the analysis of complex biological molecules at the single entity level. One particularly interesting macromolecular machine is the ribosome, responsible for translating mRNA into proteins. In this study, we use a solid-state nanopore to fingerprint 80S ribosomes and polysomes from a human neuronal cell line ...
Raveendran M, Leach AR, Hopes T, Aspden JL, Actis P.   +4 more
europepmc   +4 more sources

Fast DNA translocation through a solid-state nanopore [PDF]

Nano Letters, 2004
We report translocation experiments on double-strand DNA through a silicon oxide nanopore. Samples containing DNA fragments with seven different lengths between 2000 to 96000 basepairs have been electrophoretically driven through a 10 nm pore.
Chang H., Chen P., Deamer D. W., Doi M., Heng J. B., Kantor Y., Kasianowicz J. J., le Guillou J. C., Li J. L., Li J. L., Lubensky D. K., Mathe J., Meller A., Meller A., Nakane J. J., Padmanabhan S., Polk B. J., Ravishanker G., Sauer-Budge A. F., Smith D. E., Storm A. J.   +20 more
core   +4 more sources

Nanopore fabrication by controlled dielectric breakdown. [PDF]

PLoS ONE, 2014
Nanofabrication techniques for achieving dimensional control at the nanometer scale are generally equipment-intensive and time-consuming. The use of energetic beams of electrons or ions has placed the fabrication of nanopores in thin solid-state ...
Harold Kwok, Kyle Briggs, Vincent Tabard-Cossa   +2 more
doaj   +5 more sources

Solid-State Nanopore Single-Molecule Analysis of SARS-CoV-2 N Protein: From Interaction Exploration to Small-Molecule Antagonism [PDF]

Sensors
The COVID-19 pandemic caused by the SARS-CoV-2 virus has exposed the urgency of research on rapid and efficient virus detection and strategies to inhibit its replication. Previous studies have mostly focused on traditional immunoassay or optical methods,
Xiaoqing Zeng, Shinian Leng, Wenhao Ma, Zhenxin Wang, Huaming Zhang, Xiaowei Feng, Jianchao Li, Junsen Wang, Ting Weng, Rong Tian, Shixuan He, Shaoxi Fang, Bohua Yin, Liyuan Liang, Yajie Yin, Deqiang Wang   +15 more
doaj   +2 more sources