Nanoscale Research Letters, 2018 Solid-state nanopore has captured the attention of many researchers due to its characteristic of nanoscale. Now, different fabrication methods have been reported, which can be summarized into two broad categories: “top-down” etching technology and ...
Zhishan Yuan +5 more
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Microfluidic Systems Applied in Solid-State Nanopore Sensors [PDF]
Micromachines, 2020 Microfluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study.
Jiye Fu +4 more
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Application of Solid-State Nanopore in Protein Detection. [PDF]
Int J Mol Sci, 2020 A protein is a kind of major biomacromolecule of life. Its sequence, structure, and content in organisms contains quite important information for normal or pathological physiological process. However, research of proteomics is facing certain obstacles.
Luo Y, Wu L, Tu J, Lu Z.
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Aggregation and Oligomerization Characterization of ß-Lactoglobulin Protein Using a Solid-State Nanopore Sensor [PDF]
Sensors, 2023 Protein aggregation is linked to many chronic and devastating neurodegenerative human diseases and is strongly associated with aging. This work demonstrates that protein aggregation and oligomerization can be evaluated by a solid-state nanopore method at
Mitu C. Acharjee +7 more
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Ribosome Fingerprinting with a Solid-State Nanopore. [PDF]
ACS Sens, 2020 Abstract Nanopores hold great potential for the analysis of complex biological molecules at the single entity level. One particularly interesting macromolecular machine is the ribosome, responsible for translating mRNA into proteins.
Raveendran M +4 more
europepmc +5 more sources
Controllable Shrinking Fabrication of Solid-State Nanopores
Micromachines, 2022 Nanopores have attracted widespread attention in DNA sequencing and protein or biomarker detection, owning to the single-molecule-scale detection accuracy.
Xin Lei +4 more
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Tri‐Layer Solid‐State Nanopore Arrays with Crosstalk Suppression for High‐Throughput, Femtomolar‐Level Biosensing [PDF]
Advanced ScienceSolid‐state nanopore arrays are emerging as powerful tools for label‐free, ultrasensitive biosensing, yet their implementation has been constrained by inter‐pore crosstalk and limited fabrication uniformity.
Silu Feng +5 more
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Solid-State Nanopore Single-Molecule Analysis of SARS-CoV-2 N Protein: From Interaction Exploration to Small-Molecule Antagonism [PDF]
SensorsThe COVID-19 pandemic caused by the SARS-CoV-2 virus has exposed the urgency of research on rapid and efficient virus detection and strategies to inhibit its replication. Previous studies have mostly focused on traditional immunoassay or optical methods,
Xiaoqing Zeng +15 more
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Solid-state nanopore hydrodynamics and transport. [PDF]
Biomicrofluidics, 2019 The resistive pulse method based on measuring the ion current trace as a biomolecule passing through a nanopore has become an important tool in biotechnology for characterizing molecules. A detailed physical understanding of the translocation process is essential if one is to extract the relevant molecular properties from the current signal.
Ghosal S, Sherwood JD, Chang HC.
europepmc +4 more sources
Wafer-scale fabrication of solid-state nanopore array with a novel SpacerX process [PDF]
Microsystems & NanoengineeringSolid-state nanopores (SSNPs) have emerged as a transformative platform in nanotechnology and biotechnology, yet their application is limited by the lack of cost-effective, reproducible fabrication technology.
Lihuan Zhao +3 more
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