Results 21 to 30 of about 10,324 (277)

Screening for Group A Streptococcal disease via Solid-State Nanopore Detection of PCR Amplicons [PDF]

open access: yes, 2021
Single molecule detection methods are becoming increasingly important for diagnostic applications. Practical Early detection of disease requires sensitivity down to the level of single copies of the targeted biomarkers. Of the candidate technologies that
Robert, Slinger   +3 more
core   +1 more source

DNA Origami Characterized via Solid-State Nanopore: Insights into Nanostructure Dimensions, Rigidity and Yield [PDF]

open access: yes, 2023
Due to their programmability via specific base pairing, self-assembled DNA origami structures have proven to be useful for a wide variety of applications, including diagnostics, molecular computation, drug delivery, and therapeutics.
Hendrick, de Haan   +6 more
core   +1 more source

The Dynamics of a Molecular Plug Docked onto a Solid-State Nanopore [PDF]

open access: yes, 2018
Docking of a protein-DNA complex onto a nanopore can provide ample observation time for a detailed inspection of the complex, enabling collection of biophysical data for detection, identification, and characterization of the biomolecules.
Qiao, Li   +6 more
core   +5 more sources

Noise in solid-state nanopores [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
We study ionic current fluctuations in solid-state nanopores over a wide frequency range and present a complete description of the noise characteristics. At low frequencies ( f ≲ 100 Hz) we observe 1/ f -type of noise.
R M M, Smeets   +3 more
openaire   +2 more sources

Single-Entity Detection With TEM-Fabricated Nanopores

open access: yesFrontiers in Chemistry, 2021
Nanopore-based single-entity detection shows immense potential in sensing and sequencing technologies. Solid-state nanopores permit unprecedented detail while preserving mechanical robustness, reusability, adjustable pore size, and stability in different
Hongcheng Yang, Muhammad Saqib, Rui Hao
doaj   +1 more source

Simple Fabrication of Solid-State Nanopores on a Carbon Film

open access: yesMicromachines, 2021
Solid-state nanopores are widely used as a platform for stochastic nanopore sensing because they can provide better robustness, controllable pore size, and higher integrability than biological nanopores.
Natsumi Takai   +3 more
doaj   +1 more source

Biohybrid Membrane Formation by Directed Insertion of Aquaporin into a Solid-State Nanopore. [PDF]

open access: yesACS Appl Mater Interfaces, 2022
Biohybrid nanopores combine the durability of solid-state nanopores with the precise structure and function of biological nanopores. Particular care must be taken to control how biological nanopores adapt to their surroundings once they come into contact
Sicard F, Yazaydin AO.
europepmc   +2 more sources

Fabrication and Applications of Solid-State Nanopores [PDF]

open access: yesSensors, 2019
Nanopores fabricated from synthetic materials (solid-state nanopores), platforms for characterizing biological molecules, have been widely studied among researchers. Compared with biological nanopores, solid-state nanopores are mechanically robust and durable with a tunable pore size and geometry.
Qi Chen, Zewen Liu 0003
openaire   +3 more sources

Diameter distribution and formation mechanism of solid-state nanopores prepared by dielectric breakdown

open access: yesAIP Advances, 2021
The diameter distribution and dielectric breakdown mechanism of solid-state nanopores in a liquid environment are discussed based on the experimental results. We discussed the nanopore formation mechanism from the viewpoint of the statistical correlation
Shengfa Liang   +2 more
doaj   +1 more source

Field effect control of translocation dynamics in surround-gate nanopores

open access: yesCommunications Materials, 2021
Controlling the speed of electrophoresis across a solid-state nanopore is crucial for single-molecule sensing and sequencing. Here, a gate-controlled nanopore is able to trap and slow-down the translocation dynamics of nanoparticles by balancing the ...
Makusu Tsutsui   +6 more
doaj   +1 more source

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