Results 11 to 20 of about 20,246 (268)

Solid-state nanopore sensors

open access: yesNature Reviews Materials, 2020
Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare.
Liang Xue   +5 more
openaire   +5 more sources

Solid-state nanopore hydrodynamics and transport. [PDF]

open access: yesBiomicrofluidics, 2019
The resistive pulse method based on measuring the ion current trace as a biomolecule passing through a nanopore has become an important tool in biotechnology for characterizing molecules. A detailed physical understanding of the translocation process is essential if one is to extract the relevant molecular properties from the current signal.
Ghosal S, Sherwood JD, Chang HC.
europepmc   +4 more sources

Thermostable virus portal proteins as reprogrammable adapters for solid-state nanopore sensors [PDF]

open access: yesNature Communications, 2018
Solid state nanopores are robust but the sizing can be variable, whereas protein nanopores are precisely sized but lack robustness. Here the authors cork a solid state nanopore with the DNA-translocating portal protein from the virus G20c to obtain a ...
Benjamin Cressiot   +4 more
doaj   +2 more sources

Solid-state nanopore channels with DNA selectivity

open access: yesNature Nanotechnology, 2007
Solid-state nanopores have emerged as possible candidates for next-generation DNA sequencing devices. In such a device, the DNA sequence would be determined by measuring how the forces on the DNA molecules, and also the ion currents through the nanopore, change as the molecules pass through the nanopore.
Iqbal, Samir Muzaffar   +2 more
openaire   +6 more sources

Wafer-scale fabrication of solid-state nanopore array with a novel SpacerX process [PDF]

open access: yesMicrosystems & Nanoengineering
Solid-state nanopores (SSNPs) have emerged as a transformative platform in nanotechnology and biotechnology, yet their application is limited by the lack of cost-effective, reproducible fabrication technology.
Lihuan Zhao   +3 more
doaj   +2 more sources

Recognition of Bimolecular Logic Operation Pattern Based on a Solid-State Nanopore [PDF]

open access: yesSensors, 2020
Nanopores have a unique advantage for detecting biomolecules in a label-free fashion, such as DNA that can be synthesized into specific structures to perform computations. This method has been considered for the detection of diseased molecules.
Han Yan   +6 more
doaj   +2 more sources

Fabrication method of high energy beam for solid-state nanopore

open access: yesJin'gangshi yu moliao moju gongcheng, 2023
Solid-state nanopores have drawn the interest of numerous researchers due to their excellent mechanical properties, stability, and shape control, which have demonstrated tremendous potential in gene detection, protein detection, energy conversion ...
Wei CHEN   +5 more
doaj   +1 more source

In situsolid-state nanopore fabrication [PDF]

open access: yesChemical Society Reviews, 2021
This review summarises the development ofin situsolid-state nanopore fabrication techniques. These techniques are democratising solid-state nanopore research by providing rapid and accessible methods to fabricate nanopores.
Jasper P. Fried   +6 more
openaire   +4 more sources

Back-Side Polymer-Coated Solid-State Nanopore Sensors [PDF]

open access: yesACS Omega, 2019
Iat Wai Leong   +5 more
doaj   +2 more sources

Single-Entity Detection With TEM-Fabricated Nanopores

open access: yesFrontiers in Chemistry, 2021
Nanopore-based single-entity detection shows immense potential in sensing and sequencing technologies. Solid-state nanopores permit unprecedented detail while preserving mechanical robustness, reusability, adjustable pore size, and stability in different
Hongcheng Yang, Muhammad Saqib, Rui Hao
doaj   +1 more source

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