Results 51 to 60 of about 18,268,240 (267)

Solid-state nanopores : fabrication and applications

, 2020
Nanopores are of great interest in study of DNA sequencing, protein profiling and power generation. Among them, solid-state nanopores show obvious advantages over their biological counterparts in terms of high chemical stability and reusability as well ...
Zeng, Shuangshuang
core   +2 more sources

Size evolution and surface characterization of solid-state nanopores in different aqueous solutions

, 2012
The stability and surface evolution of solid-state nanopores in aqueous solutions are extremely important since they would get immersed in solutions during DNA translocation experiment for DNA analyses.
Zhang, HB, Lu, B, Zhao, Qing, Tang, Zhipeng, Tang, ZP, Zhang, Hengbin, Liu, Song, Yu, Dapeng, Yang, Fuhua, Liu, S, You, Liping, Qu, LJ, Yang, FH, You, LP, Zhang, Jingmin, Li, Qingtao, Zhao, Q, Qu, Lijia, Zhu, R, Li, QT, Yu, DP, Zhang, JM, Lu, Bo, Zhu, Rui   +23 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Localized Nanopore Fabrication via Controlled Breakdown

Nanomaterials, 2022
Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and other biomolecules without the need for fluorescent labeling or chemical modifications.
Cuifeng Ying, Tianji Ma, Lei Xu, Mohsen Rahmani   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Solid-state nanopores: a new platform for DNA biomarker discovery [PDF]

, 2014
Solid-state (SS) nanopores emerged as a molecular detection platform in 2001, offering many advantages over their biological counterparts, α-hemolysin nanopores (α-HL).
Marshall, Michael M., NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Sensing Single Protein Molecules with Solid-State Nanopores

, 2011
This chapter is focused on the development of experiments and theory of using solid-state nanopores for sensing single protein molecules in their native and unfolded states.
David S. Talaga, Li, Jiali, Jiali Li, Ledden, Bradley, Talaga, David S., Daniel Fologea, Bradley Ledden, Fologea, Daniel   +7 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Solid-State Nanopore Recognition and Measurement Using Shannon Entropy

IEEE Photonics Journal, 2011
Solid-state nanopores are structures that can be fabricated using the electron beam of a transmission electron microscope (TEM). Nanopores can be used to electrically detect individual DNA molecules, and they have the potential to be applied to genomic ...
Ty R. Wojcik, Diego Krapf
doaj   +1 more source