Results 201 to 210 of about 757,777 (265)

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Solid cancer-directed CAR T cell therapy that attacks both tumor and immunosuppressive cells via targeting PD-L1. [PDF]

Mol Ther Oncol
Luo Y, Gadd ME, Qie Y, Otamendi-Lopez A, Sanchez-Garavito JE, Brooks MM, Ulloa Navas MJ, Hundal T, Li S, Jones VK, Lou Y, Patel T, Dronca R, Kharfan-Dabaja MA, Dong H, Quinones-Hinojosa A, Qin H.   +16 more
europepmc   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

A human-like glutaminase-free asparaginase is highly efficacious in ASNS^low leukemia and solid cancer mouse xenograft models. [PDF]

Cancer Lett
Van Trimpont M, Schalk AM, Hofkens K, Peeters E, T'Sas S, Vandemeulebroecke K, Su Y, De Loera A, Garcia A, Chen H, Lammens T, Van Vlierberghe P, Goossens S, Lavie A.   +13 more
europepmc   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Adaptive natural killer cell expression in response to cytomegalovirus infection in blood and solid cancer. [PDF]

Heliyon
Okpoluaefe S, Ismail IS, Mohamed R, Hassan N.   +3 more
europepmc   +1 more source

“Smelltronics”—From Gas to Smell Sensing

Advanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono, Tsunaki Takahashi, Jiangyang Liu, Haruka Honda, Zeng Jing, Wataru Tanaka, Takuro Hosomi, Takeshi Yanagida   +7 more
wiley   +1 more source

Cancer Stem Cells in Solid Tumors

Current Stem Cell Research & Therapy, 2019
openaire   +2 more sources

Expression Profiles of Five Common Cancer Membrane Protein Antigens Collected for the Development of Cocktail CAR-T Cell Therapies Applicable to Most Solid Cancer Patients. [PDF]

Int J Mol Sci
Nakatsura T, Takenouchi K, Kataoka J, Ito Y, Kikuchi S, Kinoshita H, Ohnuki K, Suzuki T, Tsukamoto N.   +8 more
europepmc   +1 more source

Phase Engineering of Atomically Precise Nanoclusters (APNCs) of Gold and Beyond

Advanced Materials, EarlyView.
Engineering the structural phase of materials is of paramount importance for both fundamental research and practical applications. In this Review, we summarize the recent progress in controlling the phases of atomically precise nanoclusters (APNCs) of gold, silver and copper, as well as bimetallic systems. The phase‐enabled material properties of APNCs
Yitong Wang, Avirup Sardar, Weijie Ji, Zhongyu Liu, Rongchao Jin   +4 more
wiley   +1 more source