Results 261 to 270 of about 130,260 (303)
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Evaluation of Solid Dispersions of Clofazimine
Drug Development and Industrial Pharmacy, 2002Clofazimine (CLF) was formulated with polyethylene glycol (PEG) and polyvinyl pyrrolidone (PVP) as a solid solid dispersion (SSD) to increase the aqueous solubility and dissolution rate of the drug. Different molecular weights of PEG (1500, 4000, 6000, and 9000 Da) and PVP (14,000 and 44,000 Da) were used in different drug:carrier weight ratios (1:1, 1:
Ajit S, Narang, Anand K, Srivastava
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Solid-state characterization of nifedipine solid dispersions
International Journal of Pharmaceutics, 2002The purpose of this study is to characterize the nature and solid-state properties of a solid dispersion system of nifedipine (33.3% w/w) in a polymer matrix consisting of Pluronic F68 (33.3% w/w) and Gelucire 50/13 (33.3% w/w). The nature of nifedipine dispersed in the matrix was studied by powder X-ray diffractometry (PXRD), differential scanning ...
Sudha R, Vippagunta +3 more
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International Journal of Drug Delivery Technology, 2014
Solid dispersions are one of the most promising strategies to improve the oral bioavailability of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and hence improving drug wettability, bioavailability may be significantly improved.
Sumant Saini, Yashwant .
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Solid dispersions are one of the most promising strategies to improve the oral bioavailability of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and hence improving drug wettability, bioavailability may be significantly improved.
Sumant Saini, Yashwant .
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Journal of Chromatography A, 2000
Matrix solid-phase dispersion (MSPD) is a patented process, first reported in 1989, for conducting simultaneous disruption and extraction of solid and semi-solid samples. MSPD permits complete fractionation of the sample matrix components as well as the ability to selectively elute a single compound or several classes of compounds from the same sample.
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Matrix solid-phase dispersion (MSPD) is a patented process, first reported in 1989, for conducting simultaneous disruption and extraction of solid and semi-solid samples. MSPD permits complete fractionation of the sample matrix components as well as the ability to selectively elute a single compound or several classes of compounds from the same sample.
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Solid Dispersion: Recapitulation
Asian Journal of Pharmacy and Technology, 2020The approach to improve dissolution rate of hydrophobic drug and enhance the bioavailability, solid dispersion is one of the promising approaches in which dispersion of one or more drug substances (API) in a hydrophilic carrier at solid state is used.
Ankita G. Galam +3 more
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1991
We recently performed an extensive series of measurements of the bound electronic nonlinear refractive index n2 of a variety of solids at several wavelengths. We found that as the photon energy approached Eg (the band-gap energy), that n2 changed from positive to negative.
M Sheik-Bahae +4 more
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We recently performed an extensive series of measurements of the bound electronic nonlinear refractive index n2 of a variety of solids at several wavelengths. We found that as the photon energy approached Eg (the band-gap energy), that n2 changed from positive to negative.
M Sheik-Bahae +4 more
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International Journal of Pharmaceutics, 1993
Abstract The dissolution profiles of oxazepam from solid dispersion systems with PEG 6000 and Gelita Collagel have been investigated. The best results were obtained with spray-dried oxazepam-Collagel. X-ray diffractometry was applied to explain the changes in dissolution characteristics of oxazepam in the studied samples.
Renata Jachowicz +2 more
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Abstract The dissolution profiles of oxazepam from solid dispersion systems with PEG 6000 and Gelita Collagel have been investigated. The best results were obtained with spray-dried oxazepam-Collagel. X-ray diffractometry was applied to explain the changes in dissolution characteristics of oxazepam in the studied samples.
Renata Jachowicz +2 more
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Matrix Solid-Phase Dispersion (Mspd)
Journal of Biochemical and Biophysical Methods, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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1997
Spray drying is a cost-effective process for granulating non-oxide ceramic powders. Granulation is necessary to achieve good powder flow properties. For a dry pressing operation, good flow properties are essential to obtain uniform die filling and high green bulk densities.
Andrew G. Haerle, Kevin J. Nilsen
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Spray drying is a cost-effective process for granulating non-oxide ceramic powders. Granulation is necessary to achieve good powder flow properties. For a dry pressing operation, good flow properties are essential to obtain uniform die filling and high green bulk densities.
Andrew G. Haerle, Kevin J. Nilsen
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Properties of solid dispersions of piroxicam in polyvinylpyrrolidone
International Journal of Pharmaceutics, 1999Solid dispersions of piroxicam were prepared with polyvinylpyrrolidone (PVP) K-17 PF and PVP K-90 by solvent method. The physical state and drug:PVP interaction of solid dispersions and physical mixtures were characterized by X-ray diffraction, Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetry (DSC).
V, Tantishaiyakul +2 more
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