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Solid Lipid Nanoparticle: A Review
IOSR Journal of Pharmacy (IOSRPHR), 2012 – Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery, clinical medicine and research as well as in othervaried sciences. Solid lipid nanoparticle (SLN) dispersions have been proposed as a new type of colloidal drug carrier system suitable for intravenous ...
Ramteke K.H Joshi S.A
semanticscholar +2 more sources
Preparation of Solid Lipid Nanoparticle-Ferrous Sulfate by Double Emulsion Method Based on Fat Rich in Monolaurin and Stearic Acid. [PDF]
Nanomaterials (Basel), 2022 Subroto E +4 more
europepmc +2 more sources
Encyclopedia, 2022 Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, and prolong the circulation time of various drugs. SLNs have been applied in the oral, parenteral, transdermal, intranasal, ocular, and pulmonary drug delivery ...
Thi-Thao-Linh Nguyen, Van-An Duong
openaire +3 more sources
Solid-lipid nanoparticle formulation improves antiseizure action of cryptolepine.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021 Following the high treatment gap and massive impact of epilepsy on global health particularly in low- and middle-income countries, our study aims to investigate cryptolepine, the major alkaloid of Cryptolepis sanguinolenta as well as its solid-lipid ...
P. Mante +4 more
semanticscholar +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2021 The management of bacterial infections, especially trains of methicillin-resistant Staphylococcus aureus observe in health care settings, has markedly improved with the introduction of established drugs but using newer nano-based formulations. This study
Edwin Coleridge Stephen Naidu +5 more
doaj +1 more source
Pharmaceutics, 2023 Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin’s lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum ...
Francesca Della Sala +11 more
doaj +1 more source
A Stepwise Framework for the Systematic Development of Lipid Nanoparticles
Biomolecules, 2022 A properly designed nanosystem aims to deliver an optimized concentration of the active pharmaceutical ingredient (API) at the site of action, resulting in a therapeutic response with reduced adverse effects.
João Basso +7 more
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Pharmaceutics, 2021 Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs, even though it presents several challenges that, paradoxically, may also provide opportunities that can be exploited to achieve maximal bioavailability.
Sui Ling Janet Tan, Nashiru Billa
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Lipid-Based Nanocarriers for Ophthalmic Administration: Towards Experimental Design Implementation
Pharmaceutics, 2021 Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the anatomical and physiological barriers present in the eye, which, despite the ease of ...
Felipe M. González-Fernández +4 more
doaj +1 more source
Multifunctional nanocarriers for lung drug delivery [PDF]
, 2020 Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core +2 more sources