Results 41 to 50 of about 180,216 (329)

On the Structure of Solid Lipid Nanoparticles [PDF]

open access: yesSmall, 2019
AbstractSolid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used.
Demi L. Pink   +6 more
openaire   +2 more sources

Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]

open access: yes, 2015
Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey   +3 more
core   +2 more sources

Resveratrol in Solid Lipid Nanoparticles

open access: yesJournal of Dispersion Science and Technology, 2012
This article investigates the possibility of producing solid lipid nanoparticles (SLN) as protective vehicle of resveratrol, an antioxidant characterized by a fast trans-cis isomerization. SLN aqueous dispersions were produced by hot melt homogenization technique and characterized.
CARLOTTI, Maria Eugenia   +4 more
openaire   +2 more sources

Scalable Manufacturing Processes for Solid Lipid Nanoparticles [PDF]

open access: yesPharmaceutical Nanotechnology, 2019
Background: Solid lipid nanoparticles offer a range of advantages as delivery systems but they are limited by effective manufacturing processes. Objective: In this study, we outline a high-throughput and scalable manufacturing process for solid lipid nanoparticles.
Anderluzzi, Giulia   +3 more
openaire   +4 more sources

Bionanomedicine: A “Panacea” In Medicine? [PDF]

open access: yes, 2017
Recent advances in nanotechnology, biotechnology, bioinformatics, and materials science have prompted novel developments in the field of nanomedicine. Enhancements in the theranostics, computational information, and management of diseases/disorders are ...
Anurogo, D. (Dito)   +2 more
core   +1 more source

Gene delivery in the cornea: in vitro & ex vivo evaluation of solid lipid nanoparticle-based vectors.

open access: yesNanomedicine, 2018
AIM Inflammation is a process that underlies sight-threatening ocular surface diseases, and gene supplementation with the plasmid that encodes for p-IL10 will allow the sustained de novo synthesis of the cytokine to occur in corneal cells, and provide a ...
Mónica Vicente-Pascual   +9 more
semanticscholar   +1 more source

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles.
Neda Naseri   +2 more
doaj   +1 more source

Solid Lipid Nanoparticles (SLN)

open access: yes, 2022
Solid lipid nanoparticles (SLN) are nanocarriers in the 10–1000 nm range of a solid core, containing both hydrophilic and hydrophobic active pharmaceutical ingredients. SLNs are composed of well-tolerated and biodegradable solid lipids such as mono-, di-, and triglycerides, fatty acids, waxes, and steroids, as well as lipophilic and hydrophilic ...
Rosa-Alejandra, Hernández-Esquivel,   +3 more
openaire   +2 more sources

Development of solid lipid nanoparticle gel for transdermal delivery system of chaulmoogra oil

open access: yesExploration of Medicine, 2023
Aim: The main objective of the study was to formulate, evaluate and perform an optimization study of chaulmoogra oil-loaded solid lipid nanoparticles (SLNs) based gel.
Rabea Parveen   +4 more
doaj   +1 more source

Endocytic Uptake of Solid Lipid Nanoparticles by the Nasal Mucosa

open access: yesPharmaceutics, 2021
Nanoparticles may provide unique therapeutic opportunities when administered via the nasal cavity, yet the primary uptake and transfer pathways for these particles within the nasal mucosa are not well understood.
Ammar S. Al Khafaji, Maureen D. Donovan
doaj   +1 more source

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