Updates on the conversion of nanosuspensions to solid oral dosage forms. [PDF]
J Food Drug AnalPharmaceutical nanosuspensions, also called nanocrystals, are heterogeneous mainly aqueous dispersions of insoluble drug particles stabilised by surfactants and/or polymers. Nanosuspensions as liquid formulations suffer from instability. Solidification of nanosuspensions to solid dosage forms is a way to combine the advantages of nanocrystals with the ...
Tsiaxerli A +5 more
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Multi-Analytical Framework to Assess the In Vitro Swallowability of Solid Oral Dosage Forms Targeting Patient Acceptability and Adherence. [PDF]
Pharmaceutics, 2021 Ershad AL +4 more
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Applications of Machine Learning in Solid Oral Dosage Form Development [PDF]
Journal of Pharmaceutical Sciences, 2021 This review comprehensively summarizes the application of machine learning in solid oral dosage form development over the past three decades. In both academia and industry, machine learning is increasingly applied for multiple preformulation/formulation and process development studies.
Hao Lou, Bo Lian, Michael J. Hageman
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Development of solid paediatric oral dosage forms [PDF]
Afrika Focus, 2010 The paediatric population includes a category of patients with dynamic changes (due to the continuous body growth). Therefore their treatment requires individualized drug dosing (according to body weight) and the availability of different dosage forms for the same treatment due to different ability of paediatric patients to handle liquid (too much for ...
Egide Kayitare +2 more
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Dose dumping of modified-release solid oral dosage forms
Česká a slovenská farmacie, 2022 The presented review article is a compilation of several foreign reviews and experimental papers, as well as several authority guidelines, which deal with the phenomenon of dose dumping of solid dosage forms with modified drug release. The aim of the publication is to present this often-neglected issue to a wider domestic audience.
Tomáš, Bílik +3 more
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An evaluation of the adhesion of solid oral dosage form coatings to the oesophagus [PDF]
International Journal of Pharmaceutics, 2015 There is a requirement for the development of oral dosage forms that are adhesive and allow extended oesophageal residence time for localised therapies, or are non-adhesive for ease of swallowing. This study provides an initial assessment of the in vitro oesophageal retention characteristics of several widely utilised pharmaceutical coating materials ...
John D. Smart +3 more
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Oral Solid Dosage Form Disintegration Testing — The Forgotten Test [PDF]
Journal of Pharmaceutical Sciences, 2015 Since its inception in the 1930s, disintegration testing has become an important quality control (QC) test in pharmaceutical industry, and disintegration test procedures for various dosage forms have been described by the different pharmacopoeias, with harmonization among them still not quite complete.
Jozef, Al-Gousous, Peter, Langguth
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Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms. [PDF]
Int J Pharm X, 2023 Evgenii T +7 more
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Review: Continuous Manufacturing of Small Molecule Solid Oral Dosage Forms. [PDF]
Pharmaceutics, 2021 Wahlich J.
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Selective Laser Sintering of Solid Oral Dosage Forms with Copovidone and Paracetamol Using a CO2 Laser. [PDF]
Pharmaceutics, 2021 Gueche YA +6 more
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