Results 11 to 20 of about 5,601,796 (250)

Children's medicines in Tanzania: a national survey of administration practices and preferences. [PDF]

PLoS ONE, 2013
OBJECTIVE: The dearth of age-appropriate formulations of many medicines for children poses a major challenge to pediatric therapeutic practice, adherence, and health care delivery worldwide.
Lisa V Adams, Sienna R Craig, Elia John Mmbaga, Helga Naburi, Timothy Lahey, Cameron T Nutt, Rodrick Kisenge, Gary J Noel, Stephen P Spielberg   +8 more
doaj   +3 more sources

SILYMARIN FOOD SUPPLEMENTS – ORAL SOLID DOSAGE FORMS

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2016
Several tablet formulations containing silymarin were developed, in order to meet the requirements of different markets. Milk thistle - Silybum marianum (L.) Gaertn – standardized extracts have proven their positive effect on liver functionality plus ...
FELICIA G. GLIGOR , CARMEN M. DOBREA, CECILIA GEORGESCU , LOREDANA A. VONICA GLIGOR, ADINA FRUM, MARIA TOTAN   +5 more
doaj   +1 more source

3D printing of solid oral dosage forms: numerous challenges with unique opportunities [PDF]

, 2020
Since the FDA approval of Spritam, there has been a growing interest in the application of 3D printing in pharmaceutical science. 3D printing is a method of manufacturing involving the layer-by-layer deposition of materials to create a final product ...
ElShaer, Amr, Kayyali, Reem, Hassanin, H., Hassanin, Hany, Okafor-Muo, Ogochukwu Lilian   +4 more
core   +1 more source

Glargine insulin loaded lipid nanoparticles: Oral delivery of liquid and solid oral dosage forms [PDF]

, 2021
Background and aims: The oral administration of insulin has so far been precluded by gastro-intestinal enzyme degradation and poor intestinal absorption. Preliminary evidence for peptide uptake by the gut has recently been obtained, by our research group,
Colombino, Elena, Muntoni, Elisabetta, Anfossi, L., Anfossi, Laura, Marini, E., Battaglia, L., Porta, Massimo, Colombino, E., Battaglia, Luigi, Marini, Elisabetta, Milla, Paola, Ferraris, C., Segale, Lorena, Capucchio, M. T., Ferraris, Chiara, Muntoni, E., Capucchio, Maria T., Porta, M., Milla, P.   +18 more
core   +1 more source

Updates on the conversion of nanosuspensions to solid oral dosage forms. [PDF]

J Food Drug Anal
Pharmaceutical nanosuspensions, also called nanocrystals, are heterogeneous mainly aqueous dispersions of insoluble drug particles stabilised by surfactants and/or polymers. Nanosuspensions as liquid formulations suffer from instability.
Tsiaxerli A, Vardaka E, Moutroupidis C, Taylor KMG, Kachrimanis K, Malamatari M.   +5 more
europepmc   +3 more sources

Administration of oral dosage forms of medicines to children in a resource limited setting.

PLoS ONE, 2022
BackgroundThere are many paediatric specific challenges such as lack of age-appropriate dosage forms, inability of young children to swallow tablets and capsules and poor acceptability, during administration of oral dosage forms of medications to ...
Abarna Nadeshkumar, Gitanjali Sathiadas, Shalini Sri Ranganathan   +2 more
doaj   +1 more source

Understanding the Multidimensional Effects of Polymorphism, Particle Size and Processing for D-Mannitol Powders

Pharmaceutics, 2022
The relevance of the polymorphic form, particle size, and processing of mannitol for the mechanical properties of solid oral dosage forms was examined. Thus, particle and powder properties of spray granulated β D-mannitol, β D-mannitol, and δ D-mannitol ...
Lena Mareczek, Carolin Riehl, Meike Harms, Stephan Reichl   +3 more
doaj   +1 more source

3D-Printed Oral Dosage Forms: Mechanical Properties, Computational Approaches and Applications

Pharmaceutics, 2021
The aim of this review is to present the factors influencing the mechanical properties of 3D-printed oral dosage forms. It also explores how it is possible to use specific excipients and printing parameters to maintain the structural integrity of printed
Danae Karalia, Angeliki Siamidi, Vangelis Karalis, Marilena Vlachou   +3 more
doaj   +1 more source

3D Printing Technology as a Promising Tool to Design Nanomedicine-Based Solid Dosage Forms: Contemporary Research and Future Scope

Pharmaceutics, 2023
3D printing technology in medicine is gaining great attention from researchers since the FDA approved the first 3D-printed tablet (Spritam®) on the market.
Javed Ahmad, Anuj Garg, Gulam Mustafa, Abdul Aleem Mohammed, Mohammad Zaki Ahmad   +4 more
doaj   +1 more source

Accuracy of Dose Administered to Children Using Off-Labelled or Unlicensed Oral Dosage Forms

Pharmaceutics, 2021
The pediatric population suffers from a lack of age-appropriate medicines leading to unsafe situations when off-labelled or unlicensed drugs are used.
Guillaume Binson, Cécile Sanchez, Karen Waton, Adeline Chanat, Massimo Di Maio, Karine Beuzit, Antoine Dupuis   +6 more
doaj   +1 more source