Results 41 to 50 of about 63,264 (268)
Human Vaccines & Immunotherapeutics, 2017 Among solid organ transplant recipients, influenza infection is commonly associated with higher morbidity and mortality than immunocompetent hosts. Therefore, in these subjects influenza vaccination is of paramount importance.
Vincenzo Restivo +5 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2014 Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disease (PTLD) is one of the most serious complications associated with solid organ and hematopoietic stem cell transplantation.
Heloisa Helena de Sousa Marques +9 more
doaj +1 more source
Galectin-3 in solid organ recipients: role in graft pathology and prospects for use
Вестник трансплантологии и искусственных органов, 2023 Galectin-3 (Gal-3) is an important regulator of cell adhesion, migration, proliferation, differentiation and apoptosis under pathophysiological conditions. It plays a crucial role in diseases associated with chronic inflammation and fibrosis.
D. A. Velikiy +2 more
doaj +1 more source
Prevention and management of CMV infection in pediatric solid organ transplant recipients
Frontiers in Pediatrics, 2023 Human cytomegalovirus (CMV) remains one of the most common opportunistic infections following solid organ transplantation in children. CMV causes morbidity and mortality through direct tissue-invasive disease and indirect immunomodulatory effects.
Shanthi S. Balani +3 more
doaj +1 more source
Adenovirus in Solid Organ Transplantation
American Journal of Transplantation, 2013 Abbreviations: CDC, Centers for Disease Control and Prevention; CMV, cytomegalovirus; CTL, cytotoxic T lymphocyte; DNA, deoxyribonucleic acid; EBV, Epstein–Barr virus; FDA, Food and Drug Administration; GALT, gut associated lymphoid tissue; GVHD, graft-versus-host disease; HICPAC, Healthcare Infection Control Practices Advisory Committee; HLA, human ...
D F, Florescu, J A, Hoffman
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Cumulative Deficits Frailty Index Predicts Outcomes for Solid Organ Transplant Candidates
Transplantation Direct, 2021 Background. Despite comprehensive multidisciplinary candidacy assessments to determine appropriateness for solid organ transplantation, limitations persist in identifying candidates at risk of adverse outcomes.
Rhea A. Varughese, MD +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in Oncology, 2023 ObjectiveThis study aimed to assess the risk of maintenance immunosuppression on the post-transplant risk of malignancy across all solid organ transplant types.MethodsThis is a retrospective cohort study from a multicenter hospital system in the United ...
Reid Shaw +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source