Results 61 to 70 of about 4,346,988 (199)

Low Vapor Pressure, Low Debris Solid Target for EUV Production. [PDF]

open access: yes, 2004
An EUV radiation source that creates a stable solid filament target. The source includes nozzle assembly having a condenser chamber for cryogenically cooling a gaseous target material into a liquid state.
Michaelian, Mark   +5 more
core  

In situ transduction of target cells on solid surfaces by immobilized viral vectors

open access: yesBMC Biotechnology, 2003
Background For both in vitro and in vivo gene transfer applications, recombinant viral vectors have almost always been used free in solution. Some site-specificity of the delivery of viral vectors can be achieved by applying a solution containing viral ...
Pandori Mark W   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Analysis of hypervelocity perforation of a visco-plastic solid including the effects of target-material yield strength [PDF]

open access: yes, 1965
Hypervelocity perforation of viscoplastic solid - effects of target material yield ...
Thomson, R. G.
core  

Lysosomal transmembrane protein 5: Impact on immune cell function and implications for immune-related deficiencies

open access: yesHeliyon
Lysosomal transmembrane protein 5 (LAPTM5) is a lysosomal-associated protein that interacts with surface receptors on various immune cells, including B cells, T cells, macrophages and dendritic cells.
Peng-Peng Sun   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Electrochemical Characterization of Solid Acid Fuel Cell Electrodes [PDF]

open access: yes, 2010
The quest for high-efficiency, high-power output fuel cells can be largely equated to the quest for high-performance components (anode, cathode, electrolyte).
Sasaki, Kenji Alexander
core   +1 more source

Homeobox and Polycomb target gene methylation in human solid tumors

open access: yesScientific Reports
DNA methylation is an epigenetic mark that plays an important role in defining cancer phenotypes, with global hypomethylation and focal hypermethylation at CpG islands observed in tumors. These methylation marks can also be used to define tumor types and
Reid Blanchett   +2 more
doaj   +1 more source

Using the third state of matter: high harmonic generation from liquid targets

open access: yesNew Journal of Physics, 2014
High harmonic generation on solid and gaseous targets has been proven to be a powerful platform for the generation of attosecond pulses. Here we demonstrate a novel technique for the XUV generation on a smooth liquid surface target in vacuum, which ...
P Heissler   +10 more
doaj   +1 more source

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