Results 151 to 160 of about 649,583 (215)

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

Advanced Materials, EarlyView.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song, Melissa Cadena, Myeongsoo Kim, Euisuk Chung, Jeungyoon Lee, Zlata Brushevich, Seonghun Shin, Paul S. Pelkowski, Stanislav Y. Emelianov   +8 more
wiley   +1 more source

Ultrasound priming gated by solid tumor hallmarks to guide CAR-T therapy. [PDF]

Sci Adv
Guo T, Zhu Z, Qu Y, Yu X, Zhu L, Wang Y, Liu K, Cui J, Dong X, Yoon CW, Kilic CY, He P, Gou S, Zeng Y, Datta P, Zhou Q, Xu H, Puri IK, Liu L, Shen K, Wang Y.   +20 more
europepmc   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Programmable-bacteria-macrophage backpacks for enhanced solid tumor therapy via mechanobiological interplay. [PDF]

Cell Rep Med
Fan Z, Chen P, Zuo S, Cai K, Li S, Qin H, Li R, Lee K, Chen T, Jin C, Li J, Chen Y.   +11 more
europepmc   +1 more source

Synchronized Ablation of Multifocal Tumors Enabled by Multi‐Channel Lanthanide Nanocomposites

Advanced Materials, EarlyView.
A multi‐channel lanthanide nanocomposite enables orthogonal monitoring of tumor pH, glutathione, and temperature to guide customized therapy. Real‐time luminescence readouts determine a single irradiation protocol that synchronizes drug release and photothermal treatment, allowing efficient ablation of multifocal tumors while minimizing overtreatment ...
Fang Li, Zheng Wei, Francesco G. Mutti, Hong Zhang, Felix F. Loeffler, Yuxin Liu, Xingjun Zhu   +6 more
wiley   +1 more source

An inducible signal 1 booster overcomes limited access to antigen for solid tumor cell therapy. [PDF]

Mol Ther Oncol
Radecki KC, Manry D, Kirsh C, Kumar N, McLeod E, Krishnagiri A, Flynn AD, Sima A, Oh J, Partin AC, DiAndreth B, Kamb A.   +11 more
europepmc   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

The role of RARG in solid tumor progression and therapeutic potential. [PDF]

Discov Oncol
Guo S, Han H, Ding B, Zhang W, Qin L.
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source