Brain tumors induced in rats by human adenovirus type 12 [PDF]
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Ogawa, Katsuo +5 more
core +1 more source
Management of germ cell tumors in children: Approaches to cure [PDF]
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Schneider, D. T. +9 more
core +1 more source
Tumor–platelet interaction in solid tumors [PDF]
AbstractElevated platelet counts in patients diagnosed with malignant tumors were first described more than 100 years ago. Today it is well known that in many types of solid tumors, thrombocytosis at the time of diagnosis is associated with shorter survival.
Daniel, Buergy +3 more
openaire +2 more sources
Benign solid liver tumors are frequently discovered during routine sonographic examinations. As a rule, malignant tumors can be excluded using contrast medium-based sectional imaging; however, unclear cases can represent a diagnostic challenge.
Neumann, U.P. +3 more
core +1 more source
Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration [PDF]
The therapeutic potential of epigallocatechin gallate, a green tea polyphenol with anti-cancer properties, is limited by its inability to specifically reach tumors following intravenous administration.
Dufès, Christine +7 more
core +4 more sources
Drug combinations are key to circumvent resistance mechanisms compromising response to single anti-cancer targeted therapies. The implementation of combinatorial approaches involving MEK1/2 or KRASG12C inhibitors in the context of KRAS-mutated lung ...
Irati Macaya +31 more
doaj +1 more source
Specific loss of chromosomes 1, 2, 6, 10, 13, 17, and 21 in chromophobe renal cell carcinomas revealed by comparative genomic hybridization [PDF]
We analyzed 19 chromophobe renal cell carcinomas by means of comparative genomic hybridization. Two tumors revealed no numerical abnormalities. In the remaining 17 cases we found loss of entire chromosomes with underrepresentation of chromosome 1 ...
Speicher, Michael R. +7 more
core +1 more source
Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer
Novel antibody-drug conjugates against HER2 are showing high activity in HER2-negative breast cancer (BC) with low HER2 expression (i.e., 1+ or 2+ and lack of ERBB2 amplification). However, the clinical and molecular features of HER2-low BC are yet to be
Francesco Schettini +26 more
doaj +1 more source
Feasibility of Photofrin II as a radiosensitizing agent in solid tumors - Preliminary results [PDF]
Background: Photofrin II has been demonstrated to serve as a specific and selective radiosensitizing agent in in vitro and in vivo tumor models. We aimed to investigate the feasibility of a clinical application of Photofrin II.
Wilkowski, Ralf +7 more
core +1 more source
Application of X-ray Microtomography to Quantify the Liquid Fraction of M2 Steel for Semi-solid Forming process [PDF]
Thixoforging, one variant of semi-solid metal processing in which the metallic alloys are processed at low liquid fraction (0.1< Fl < 0.3), is used to produce complex parts with high mechanical properties.
GU, Guochao +4 more
core +1 more source

