Results 181 to 190 of about 2,494,673 (310)

Bioengineered cell therapies for pediatric solid tumors: unmet needs and a measurement-integrated approach. [PDF]

Prog Biomed Eng (Bristol)
Sandoval-Castellanos AM, Ahn YR, Canter RJ, Brown EG, Kim J.   +4 more
europepmc   +1 more source

Solid Pseudopapillary Pancreatic Tumor – Tumor of Frantz [PDF]

Madridge Journal of Surgery, 2019
Valentina Madjova, Vasil Bozhkov, Plamen Chernopolsky, Rossen Madjov   +3 more
openaire   +2 more sources

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Case Report: Primed dendritic cell immunotherapy for multiple solid tumors. [PDF]

Front Immunol
Jones J, Alrabaa A, Decker W, Ferbeyre L, Viramontes G, Gonzalez R, Angulo E, Zamudio A, Hernandez R, Noga S, Hernandez-Reyes S, Zhang P, Smith D, Karamanian A, Tamara L, Greenwood D, Halpert M.   +16 more
europepmc   +1 more source

A Novel Drug‐Loaded Porous Parylene Electrode for Targeted Anti‐Inflammatory Therapy and Hearing Preservation in Cochlear Implantation

Advanced Healthcare Materials, EarlyView.
A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang, Ying‐Chang Lu, Yu‐Ming Chang, Yen‐Hui Chan, Hong‐Yu Yan, Yi‐Shan Lee, Pei‐Hsuan Lin, Cheng‐Yu Hsieh, Chuan‐Jen Hsu, Tien‐Chen Liu, Hsien‐Yeh Chen, Chen‐Chi Wu   +11 more
wiley   +1 more source

Progress in cell-based immunotherapies for solid tumors. [PDF]

Discov Oncol
Zhang L, Zhang D, Wang B.
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Imbalances of mitochondrial dynamics in solid tumors. [PDF]

Oncogenesis
Roskam C, Roessler HRK, Medema JP, Bijlsma MF.   +3 more
europepmc   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

CCL3 and IL-7 Synergistically Enhance CAR-T Efficacy in Solid Tumors. [PDF]

Adv Sci (Weinh)
Chen H, Luo X, Gao H, Ke Y, Zhan Y, Xu X, Xiong X, Wei F, Yang S, Liu Z, Yu B, Huang Z, Bian Y.   +12 more
europepmc   +1 more source