Results 141 to 150 of about 461,523 (268)

Bispecific Antibodies in Solid Tumors: Mechanistic Insights, Clinical Advances, and Future Directions. [PDF]

J Immunother Precis Oncol
Almosa R, Mendoza MM, Tang TY, Stephen B.   +3 more
europepmc   +1 more source

Solid Pseudopapillary Pancreatic Tumor – Tumor of Frantz [PDF]

Madridge Journal of Surgery, 2019
Valentina Madjova, Vasil Bozhkov, Plamen Chernopolsky, Rossen Madjov   +3 more
openaire   +2 more sources

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Longitudinal methylated ctDNA increases predict immunotherapy progression across solid tumors. [PDF]

J Liq Biopsy
Anees M, Wagner PL, Omstead A, Grayhack E, Sherry C, McDaniel LD, Varga MG, Hosseiny SMH, Laframboise W, Nakayama J, Krivak T, Weksler B, Dadgar N, Qazi SU, Bahary N, Bartlett DL, Tsao DS, Zaidi AH.   +17 more
europepmc   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Liposome-Encapsulated Carfilzomib as a Radiosensitizer in Solid Tumors. [PDF]

Mol Pharm
Molinaro M, Saha P, Skrodzki D, Machtay M, Pan D.   +4 more
europepmc   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Retraction Note: Hurdles to breakthrough in CAR T cell therapy of solid tumors. [PDF]

Stem Cell Res Ther
Marofi F, Achmad H, Bokov D, Abdelbasset WK, Alsadoon Z, Chupradit S, Suksatan W, Shariatzadeh S, Hasanpoor Z, Yazdanifar M, Shomali N, Khiavi FM.   +11 more
europepmc   +1 more source

Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov‐Excited Luminescence Imaging (CELI) of Oxygen

Advanced Healthcare Materials, EarlyView.
Biocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Simin Belali, Marien Iliza Ochoa Mendoza, Matthew S. Reed, Danylo Mykhalchuk, Annemarie Lang, Joel D. Boerckel, Brian W. Pogue, Sergei A. Vinogradov   +7 more
wiley   +1 more source

Amino Acids as Targets for Immunotherapy against Solid Tumors. [PDF]

Cell Biochem Biophys
da Costa KVV, Passos GA, Botelho RJS, Ruza MSV, Dias-Lopes G, Silva RCMC.   +5 more
europepmc   +1 more source