Results 11 to 20 of about 2,494,673 (310)

A molecular map of mesenchymal tumors [PDF]

, 2005
Background: Bone and soft tissue tumors represent a diverse group of neoplasms thought to derive from cells of the mesenchyme or neural crest. Histological diagnosis is challenging due to the poor or heterogenous differentiation of many tumors, resulting
Flanagan, AM, Guiliano, D, Boshoff, C, McLean, S, Frow, R, Sebire, N, Henderson, SR, Stephen R Henderson, Nick Athanasou, Vujovic, S, Anderson, J, Athanasou, N, John Anderson, Neil Sebire, David Guiliano, Sean McLean, Nadege Presneau, Richard Frow, Jeremy Whelan, Whelan, J, Adrienne M Flanagan, Presneau, N, Sonja Vujovic, Chris Boshoff   +23 more
core   +1 more source

Modeling the Mechanobiology of Cancer Cell Migration Using 3D Biomimetic Hydrogels

Gels, 2021
Understanding how cancer cells migrate, and how this migration is affected by the mechanical and chemical composition of the extracellular matrix (ECM) is critical to investigate and possibly interfere with the metastatic process, which is responsible ...
Xabier Morales, Iván Cortés-Domínguez, Carlos Ortiz-de-Solorzano   +2 more
doaj   +1 more source

t(12;15)(p13;q25) ETV6/NTRK3 in solid tumors [PDF]

, 2020
Review on t(12;15)(p13;q25) in solid tumors, with data on clinics, and the genes ...
Huret, Jean-Loup
core   +1 more source

Table_1_Therapeutic exercise interventions in pediatric survivors of brain cancer and other solid tumors: A scoping review.pdf [PDF]

, 2022
BackgroundImproved survival rates for children with solid tumors presents an ongoing challenge of how to maximize quality of survivorship and effectively manage the short- and long-term complications of disease and treatment.
Sandler, Carolina X, Emmah Baque (3572792), Bradford, Natalie K, Sandler, Carolina X. (R20531), Stewart G. Trost (8871872), Kohler, Brooke E., Trost, Stewart G, Brooke E. Kohler (10217341), Carolina X. Sandler (10217344), Natalie K. Bradford (13808164), Trost, Stewart G., Bradford, Natalie K., Sandler, Carolina X., Baque, Emmah, Kohler, Brooke E   +14 more
core   +1 more source

Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma

Genome Medicine, 2021
Background Malignant pleural mesothelioma (MPM) is a heterogeneous cancer. Better knowledge of molecular and cellular intra-tumor heterogeneity throughout the thoracic cavity is required to develop efficient therapies.
Clément Meiller, François Montagne, Theo Z. Hirsch, Stefano Caruso, Julien de Wolf, Quentin Bayard, Jean-Baptiste Assié, Léa Meunier, Yuna Blum, Lisa Quetel, Laure Gibault, Ecaterina Pintilie, Cécile Badoual, Sarah Humez, Françoise Galateau-Sallé, Marie-Christine Copin, Eric Letouzé, Arnaud Scherpereel, Jessica Zucman-Rossi, Françoise Le Pimpec-Barthes, Marie-Claude Jaurand, Didier Jean   +21 more
doaj   +1 more source

Chronotherapeutics for Solid Tumors

Pharmaceutics, 2023
Circadian rhythms are internal manifestations of the 24-h solar day that allow for synchronization of biological and behavioral processes to the external solar day. This precise regulation of physiology and behavior improves adaptive function and survival.
Claire O. Kisamore, Brittany D. Elliott, A. Courtney DeVries, Randy J. Nelson, William H. Walker   +4 more
openaire   +3 more sources

Interaction of host immunity with HER2-targeted treatment and tumor heterogeneity in HER2-positive breast cancer

Journal for ImmunoTherapy of Cancer, 2019
Growing evidence suggests a clear role of the host immune system in HER2+ breast cancer. In addition, HER2+ breast cancer is generally considered more immunogenic than hormone receptor-positive (HR+)/HER2-, and specific molecular HER2+ subgroups (e.g ...
Gaia Griguolo, Tomás Pascual, Maria Vittoria Dieci, Valentina Guarneri, Aleix Prat   +4 more
doaj   +1 more source

MicroRNAs in Solid Tumors [PDF]

Journal of Surgical Research, 2009
MicroRNAs (miRNAs or miRs) are small, noncoding RNAs (approximately 20-22 nucleotides) that have critical functions in cell proliferation, apoptosis, and differentiation. These evolutionarily conserved RNA sequences are the result of a complex sequence of processing steps, which can regulate the expression of tens, and even hundreds, of genes.
Mary, Dillhoff, Sylwia E, Wojcik, Mark, Bloomston   +2 more
openaire   +2 more sources

Metastasis and Tumor Cell Migration of Solid Tumors [PDF]

Cancers, 2021
The developmental process of local and distant metastases represents the major and defining trait of malignant tumors, whereby tumor cells sustain the capability to migrate from the initial tumor site, seed, and grow at a location other than that of the initial tumor [...]
Jens Hoeppner, Peter Bronsert
openaire   +3 more sources

Numerical simulation of solid tumor blood perfusion and drug delivery during the “vascular normalization window” with antiangiogenic therapy [PDF]

, 2011
This Article is provided by the Brunel Open Access Publishing Fund - Copyright @ 2011 Hindawi PublishingTo investigate the influence of vascular normalization on solid tumor blood perfusion and drug delivery, we used the generated blood vessel network ...
Long, Q, Cai, Y, Quan Long, Yu Zhou, Lv, J, Zhou, Y, Wei Yao, Xu, S, Yao, W, Shi-xiong Xu, Jie Lv, Cao, J, Jin-feng Cao, Yan Cai   +13 more
core   +1 more source