Results 51 to 60 of about 385,356 (336)

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Review on Cement Stabilization/Solidification of Municipal Solid Waste Incineration Fly Ash

open access: yesAdvances in Materials Science and Engineering, 2018
Municipal solid waste incineration (MSWI) fly ash must be treated properly prior to being disposed in the security landfill due to its serious pollution toxicity.
C. Fan, Baomin Wang, Tingting Zhang
semanticscholar   +1 more source

Iron melting curve with a tricritical point

open access: yes, 2007
Solidification as a first order phase transition is described in the Landau theory by the same equation as tricritical phenomena. Here, the solidification or melting temperature against pressure curve is modelled to end at a tricritical point.
Aitta, A.
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Degassing of Aluminum Alloy Melts by High Shear Melt Conditioning Technology: An Overview

open access: yesMetals, 2022
The search for more efficient methods for degassing aluminum alloy melts has always been of great interest for the metal industry because the presence of hydrogen and oxides in the melts’ prior casting was detrimental to the integrity and properties of ...
Jaime Lazaro-Nebreda   +7 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Phase-selective recrystallization makes eutectic high-entropy alloys ultra-ductile

open access: yesNature Communications, 2022
The ever most widely used eutectic alloys often suffer from limited ductility. Here the authors propose a distinctive concept of phase-selective recrystallization to significantly improve their ductility and strength and pave the way for new applications
Qingfeng Wu   +5 more
doaj   +1 more source

In-situ steel solidification imaging in continuous casting using magnetic induction tomography [PDF]

open access: yes, 2020
: Solidification process in continuous casting is a critical part of steel production. The speed and quality of the solidification process determines the quality of final product.
Barbero, J   +6 more
core   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Segregation-dislocation self-organized structures ductilize a work-hardened medium entropy alloy

open access: yesNature Communications
Dislocations are the intrinsic origin of crystal plasticity. However, initial high-density dislocations in work-hardened materials are commonly asserted to be detrimental to ductility according to textbook strengthening theory.
Bojing Guo   +13 more
doaj   +1 more source

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