Results 61 to 70 of about 108,716 (266)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Enhancing creep rupture life prediction of high‐temperature titanium alloys using convolutional neural networks

Materials Genome Engineering Advances
Prediction of creep rupture life of high‐temperature titanium alloys is crucial for their practical applications. The efficient representations (features) of the information encoded in the data are essential to achieve an accurate prediction model. Here,
Bangtan Zong, Jinshan Li, Changlu Zhou, Ping Wang, Bin Tang, Ruihao Yuan   +5 more
doaj   +1 more source

Electrochemical Performance of Chitosan Oligosaccharide/Carbon Nanotube Composite for Detection of Trace Copper(II) Ion

International Journal of Electrochemical Science, 2017
Chitosan oligosaccharide (COS)/multi-walled carbon nanotube (MWCNT) composite was prepared by electrostatic self-assembly method. The thickness of COS uniformly enwrapped on the surface of MWCNTs is around 3.3 nm.
Tingkai Zhao, Xianglin Ji, Wenbo Jin, Shasha Guo, Yuanbo Cheng, Xuan Wang, Alei Dang, Hao Li, Tiehu Li   +8 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Phase Transformation Kinetics of a FCC Al_0.25CoCrFeNi High-Entropy Alloy during Isochronal Heating

Metals, 2018
The phase transformation kinetics of a face-centered-cubic (FCC) Al0.25CoCrFeNi high-entropy alloy during isochronal heating is investigated by thermal dilation experiment.
Jun Wang, Chen Wei, Haoxue Yang, Tong Guo, Tingting Xu, Jinshan Li   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Metastable microstructure evolution and grain refinement in a Low-Ta containing γ-TiAl alloy through heat treatment

Journal of Materials Research and Technology
The paper comprehensively describes the evolution of metastable microstructures in a cast low-Ta-containing γ-TiAl alloy during cooling-tempering-lamellarization heat treatments. The behavior and mechanism of microstructure refinement are discussed.
Zitong Gao, Rui Hu, Hang Zou, Jinguang Li, Mi Zhou, Xian Luo   +5 more
doaj   +1 more source

The Effect of Thermal Cycling Treatments on the Thermal Stability and Mechanical Properties of a Ti-Based Bulk Metallic Glass Composite

Metals, 2016
The effect of thermal cycling treatments on the thermal stability and mechanical properties of a Ti48Zr20Nb12Cu5Be15 bulk metallic glass composite (BMGC) has been investigated.
Fan Bu, Jun Wang, Liyuan Li, Hongchao Kou, Xiangyi Xue, Jinshan Li   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source