Results 101 to 110 of about 289,770 (195)

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Homogeneity and Thermal Stability of Sputtered Al_0.7Sc_0.3N Thin Films. [PDF]

Materials (Basel), 2023
Carmona-Cejas JM, Mirea T, Nieto J, Olivares J, Felmetsger V, Clement M.   +5 more
europepmc   +1 more source

Physics‐Aware Machine‐Learning‐Driven Inverse Design of Broadband Ultra‐Open Acoustic Metamaterials

Advanced Science, EarlyView.
A physics‐aware machine‐learning framework enables inverse design of ultra‐open acoustic silencers by decoupling spectral and radial design spaces. The approach rapidly identifies broadband, compact, and highly ventilated architectures, while revealing hidden linear design rules that link geometry, impedance matching, and acoustic performance.
Zhiwei Yang, Mengyu Li, Xiaohang Xie, Ao Chen, Thomas G. Bifano, Xin Zhang   +5 more
wiley   +1 more source

High-Order Harmonic Film Bulk Acoustic Resonator Based on a Polymer Reflector. [PDF]

Sensors (Basel), 2022
Hu Y, Dong B, Lei L, Wang Z, Ruan S.
europepmc   +1 more source

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

A review of piezoelectric MEMS sensors and actuators for gas detection application. [PDF]

Discov Nano, 2023
Ba Hashwan SS, Khir MHM, Nawi IM, Ahmad MR, Hanif M, Zahoor F, Al-Douri Y, Algamili AS, Bature UI, Alabsi SS, Sabbea MOB, Junaid M.   +11 more
europepmc   +1 more source

Sustained Self‐Powered Real‐Time Vibration Monitoring Through Integrated Nonlinear Harvesting and Energy‐Aware Wireless Sensing

Advanced Science, EarlyView.
A self‐powered vibration sensing platform integrates a quasi‐zero‐stiffness piezoelectric harvester, synchronized electric charge extraction, energy management, and wireless ADC acquisition. Ambient vibration is simultaneously harvested as energy and digitized as information, enabling sustained real‐time waveform monitoring without external power.
Yizhou Li, Ye Zhang, Hao Tang, Yaozi Zheng, Yawei Wang, Chaoyang Zhao, Liwei Dong, Dewen Yu, Junlei Wang, Chunbo Lan, Guobiao Hu   +10 more
wiley   +1 more source

Microwave Diamond-Based HBAR as a Highly Sensitive Sensor for Multiple Applications: Acoustic Attenuation in the Mo Film. [PDF]

Sensors (Basel), 2023
Sorokin B, Asafiev N, Yashin D, Luparev N, Golovanov A, Kravchuk K.   +5 more
europepmc   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source

A multi-port optical microfiber coil resonator

A new type of multi-port optical microfiber resonator is presented. The coupler-based coil resonator was fabricated by coiling a four port microfiber coupler around a low index support rod and then embedding the resulting device in a low refractive index
Brambilla, Gilberto, Ismaeel, Rand, Al-Saab, Feras, Jung, Yongmin, Lee, Timothy   +4 more
core   +1 more source