Impact of IgG subclass on molecular properties of monoclonal antibodies
mAbs, 2021 Immunoglobulin G-based monoclonal antibodies (mAbs) have become a dominant class of biotherapeutics in recent decades. Approved antibodies are mainly of the subclasses IgG1, IgG2, and IgG4, as well as their derivatives. Over the decades, the selection of
Yu Tang +5 more
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Process Optimization and Functional Determination of Peanut Protein by Complex Enzymatic Extraction
Liang you shipin ke-ji, 2023 Peanuts were hydrolyzed step by step with various enzymes to prepare protein powder. Using peanuts as raw materials, protein extraction rate response value, enzyme addition amount, temperature, and pH as experimental factors, were used to establish a ...
MA He, ZHANG Wen-yu, LIU Chang-jin
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Image-based dissolution analysis for tracking the surface stability of amorphous powders
ADMET and DMPK, 2020 Poor solubility of crystalline drugs can be overcome by amorphization – the production of high-energy disordered solid with improved solubility.
Jernej Štukelj +4 more
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Frontiers in Immunology, 2020 β-Glucans are a heterogeneous group of glucose polymers with a common structure comprising a main chain of β-(1,3) and/or β-(1,4)-glucopyranosyl units, along with side chains with various branches and lengths.
Biao Han +5 more
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The effect of temperature and ligand structure on the solubility of gold nanoparticles
Materials Research Express, 2021 In order to investigate the effect of ligands structure, and temperature on the solubility of the smallest crystallographic gold nanoparticle, Au _18 S _14 , quantum mechanical calculations, and molecular dynamics simulations have been performed. Ligands
Mandana Tarakame Samani +1 more
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Poultry Science, 2020 The effect of high-pressure processing (200 MPa, 10 min) on the solubility of chicken breast myosin with 25% molar substitution of Na+ by 3 anion types of potassium salts (KCl, K-lactate, and K-citrate) was investigated. The results showed that the lower
Ying Zhou +5 more
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Effects of CO32− and OH− on the solubility, metastable zone width and nucleation kinetics of borax decahydrate [PDF]
Royal Society Open Science, 2019 Measurements of the solubility and metastable zone width (MZW) of borax decahydrate in sodium carbonate and sodium hydroxide aqueous were obtained. The onsets of nucleation were detected by the turbidity technique with the temperature range from 285 to ...
Jing Chen +4 more
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Solubility improvement of progesterone from solid dispersions prepared by solvent evaporation and co-milling [PDF]
, 2020 The aim of this contribution was to evaluate the impact of processing methods and polymeric carriers on the physicochemical properties of solid dispersions of the poorly soluble drug progesterone (PG). Five polymers: hydroxypropyl methylcellulose (HPMC),
Al-Obaidi, Hisham +3 more
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Solubility of dicarbohydrazide bis[3-(5-nitroimino-1,2,4-triazole)] in common pure solvents and binary solvents at different temperatures [PDF]
Royal Society Open Science, 2019 The solubility of dicarbohydrazide bis[3-(5-nitroimino-1,2,4-triazole)] (DCBNT) was first measured under the different pure solvents and binary solvents by the dynamic method over the temperature range of 290–360 K at atmospheric pressure. Results in all
Jianrong Ren +3 more
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Novel multi-component crystals of berberine with improved pharmaceutical properties
IUCrJ, 2023 As an extremely popular natural product, berberine (BER) is mainly used for gastroenteritis and diarrhoea caused by bacteria. Research has also revealed the potent and extensive pharmacological properties of BER including its anti-arrhythmic, anti-tumour,
Guoshun Zhang +6 more
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