Results 1 to 10 of about 1,433,465 (359)
Protein Design: From the Aspect of Water Solubility and Stability
Chemical Reviews, 2022 Water solubility and structural stability are key merits for proteins defined by the primary sequence and 3D-conformation. Their manipulation represents important aspects of the protein design field that relies on the accurate placement of amino acids ...
Rui Qing, Shilei Hao, Arthur O Zalevsky
exaly +2 more sources
Solubility of Cyclodextrins and Drug/Cyclodextrin Complexes
Molecules, 2018 Cyclodextrins (CDs), a group of oligosaccharides formed by glucose units bound together in a ring, show a promising ability to form complexes with drug molecules and improve their physicochemical properties without molecular modifications.
Phennapha Saokham +2 more
exaly +2 more sources
Pharmaceutics, 2022 Glasdegib is a recently approved drug for the treatment of acute myeloid leukemia. It is formulated and marketed in monomaleate salt form. In our investigation, we were able to prepare a glasdegib dimaleate form, which could, in theory, exist in double ...
Boris Peklar +6 more
doaj +1 more source
Image-based dissolution analysis for tracking the surface stability of amorphous powders
ADMET and DMPK, 2020 Poor solubility of crystalline drugs can be overcome by amorphization – the production of high-energy disordered solid with improved solubility.
Jernej Štukelj +4 more
doaj +1 more source
On the Solubility and Stability of Polyvinylidene Fluoride
Polymers, 2021 This literature review covers the solubility and processability of fluoropolymer polyvinylidine fluoride (PVDF). Fluoropolymers consist of a carbon backbone chain with multiple connected C–F bonds; they are typically nonreactive and nontoxic and have ...
J. Marshall +8 more
semanticscholar +1 more source
Solids, colloids, and the hydrolysis of tetravalent uranium in chloride media
Frontiers in Nuclear Engineering, 2023 Understanding of the properties of dissolution and precipitation of Uranium under reducing geochemical conditions is important in radioactive waste management and assessments of natural uranium deposits. The mechanism of forming UO2+y from U(VI) and U(IV)
B. Grambow +4 more
doaj +1 more source
Журнал органічної та фармацевтичної хімії, 2023 In this paper, it is proposed to consider a new method developed for studying the kinetics of release of substances that are poorly soluble in aqueous media on the example of quercetin. The study object was the drug containing plant bioactive components –
Nataliia V. Khanina +3 more
doaj +1 more source
ADMET and DMPK, 2020 <p class="ADMETabstracttext">Solubility is a fundamental protein property that has important connotations for therapeutics and use in diagnosis. Solubility of many proteins is low and affect heterologous overexpression of proteins, formulation of products and their stability.
openaire +4 more sources
THE SOLUBILITY OF GYPSUM. [PDF]
Journal of the American Chemical Society, 1902 n ...
Hulett, George A., Allen, Lucius E.
openaire +3 more sources
Pharmaceutics, 2023 Zinc diethyldithiocarbamate (Zn (DDC)2), a disulfiram metabolite (anti-alcoholism drug), has shown a strong anti-cancer activity in vitro. However, its application was limited by its low aqueous solubility and rapid metabolism.
Ayşe Kaya +6 more
doaj +1 more source