Results 21 to 30 of about 379,425 (268)

Solid dispersion complex triclabendazole preparations with succinic acid and their fasciolocidal activity

open access: yesРоссийский паразитологический журнал, 2023
The purpose of the research is to test the efficacy of triclafascid and two solid dispersion complex preparations based on the triclabendazole substance against fasciolosis in cattle and sheep. Materials and methods.
M. B. Musaev   +4 more
doaj   +1 more source

Modifcation of anthelmintic drugs by nanotechnology (review)

open access: yesРоссийский паразитологический журнал, 2022
The purpose of the research is to analyze and summarize the literature data and the results of our own studies on the use of drug delivery systems and methods for increasing the solubility and efcacy of anthelmintic drugs.Helminthoses are one of the most
A. I. Varlamova   +3 more
doaj   +1 more source

Versatile Solid Modifications of Multicomponent Pharmaceutical Salts: Novel Metformin–Rhein Salts Based on Advantage Complementary Strategy Design

open access: yesPharmaceutics, 2023
This study aimed to develop an effective treatment for diabetes and diabetic complications, based on the advantage complementary strategy of drug–drug salt, by designing and synthesizing the multicomponent molecular salts containing metformin (MET) and ...
Mingchao Yu   +11 more
doaj   +1 more source

Effect of Solvent Composition on Solubility, Thermodynamics, Metastable Zone Width (MSZW) and Crystal Habit of L-Ascorbic Acid

open access: yesCrystals, 2022
This work investigates the effect of different solvent systems on solubility, thermodynamics, metastable zone width (MSZW), and crystal habit of ascorbic acid, in order to help optimize its crystallization process.
Jyoti Yadav   +4 more
doaj   +1 more source

A Novel Cocrystal of Daidzein with Piperazine to Optimize the Solubility, Permeability and Bioavailability of Daidzein

open access: yesMolecules
It is well known that daidzein has various significant medicinal values and health benefits, such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, cholesterol lowering, neuroprotective, cardioprotective and so on.
Zhipeng Wang   +9 more
doaj   +1 more source

Synthesis of Purine-Based Ionic Liquids and Their Applications

open access: yesMolecules, 2021
Bio-based ionic liquids (ILs) are being increasingly sought after, as they are more sustainable and eco-friendly. Purines are the most widely distributed, naturally occurring N-heterocycles, but their low water-solubility limits their application.
Ana R. F. Carreira   +8 more
doaj   +1 more source

Solubility of Melanins [PDF]

open access: yesNature, 1952
IN further attempts to find a solvent for melanin which would be of use in histological work, the following substances have been found to dissolve, in the cold, the pigments extracted from the ink sac of Sepia officinalis and melanoma tissue, and those prepared from adrenaline and 3,4-dihydroxyphenylalanine (dopa): ethylene glycol monomethyl ether ...
openaire   +2 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Solids Turn into Liquids—Liquid Eutectic Systems of Pharmaceutics to Improve Drug Solubility

open access: yesPharmaceuticals, 2022
The low solubility of active pharmaceutical ingredients (APIs) is a problem in pharmaceutical development. Several methodologies can be used to improve API solubility, including the use of eutectic systems in which one of the constituents is the API ...
Mafalda C. Sarraguça   +3 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy