Results 21 to 30 of about 379,425 (268)
The purpose of the research is to test the efficacy of triclafascid and two solid dispersion complex preparations based on the triclabendazole substance against fasciolosis in cattle and sheep. Materials and methods.
M. B. Musaev +4 more
doaj +1 more source
Modifcation of anthelmintic drugs by nanotechnology (review)
The purpose of the research is to analyze and summarize the literature data and the results of our own studies on the use of drug delivery systems and methods for increasing the solubility and efcacy of anthelmintic drugs.Helminthoses are one of the most
A. I. Varlamova +3 more
doaj +1 more source
This study aimed to develop an effective treatment for diabetes and diabetic complications, based on the advantage complementary strategy of drug–drug salt, by designing and synthesizing the multicomponent molecular salts containing metformin (MET) and ...
Mingchao Yu +11 more
doaj +1 more source
This work investigates the effect of different solvent systems on solubility, thermodynamics, metastable zone width (MSZW), and crystal habit of ascorbic acid, in order to help optimize its crystallization process.
Jyoti Yadav +4 more
doaj +1 more source
It is well known that daidzein has various significant medicinal values and health benefits, such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, cholesterol lowering, neuroprotective, cardioprotective and so on.
Zhipeng Wang +9 more
doaj +1 more source
Synthesis of Purine-Based Ionic Liquids and Their Applications
Bio-based ionic liquids (ILs) are being increasingly sought after, as they are more sustainable and eco-friendly. Purines are the most widely distributed, naturally occurring N-heterocycles, but their low water-solubility limits their application.
Ana R. F. Carreira +8 more
doaj +1 more source
IN further attempts to find a solvent for melanin which would be of use in histological work, the following substances have been found to dissolve, in the cold, the pigments extracted from the ink sac of Sepia officinalis and melanoma tissue, and those prepared from adrenaline and 3,4-dihydroxyphenylalanine (dopa): ethylene glycol monomethyl ether ...
openaire +2 more sources
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Solids Turn into Liquids—Liquid Eutectic Systems of Pharmaceutics to Improve Drug Solubility
The low solubility of active pharmaceutical ingredients (APIs) is a problem in pharmaceutical development. Several methodologies can be used to improve API solubility, including the use of eutectic systems in which one of the constituents is the API ...
Mafalda C. Sarraguça +3 more
doaj +1 more source
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source

