Results 231 to 240 of about 1,983,588 (386)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

pH-Dependent Solubility and Dissolution Behavior of Carvedilol—Case Example of a Weakly Basic BCS Class II Drug

open access: yesAAPS PharmSciTech, 2016
Rania Hamed   +7 more
semanticscholar   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Solubility Enhancement Of Poorly Soluble Drug

open access: yes
The purpose of this evaluation was to enhance the solubility and bioavailability of poorly soluble medications through a variety of methods such as physical, chemical, and other modifications or techniques. Solubility refers to the maximum amount of solute that can dissolve in a specific amount of solvent or solution at a given temperature.
openaire   +2 more sources

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