Results 81 to 90 of about 609,910 (308)

Preparation and solubility of hydroxyapatite

open access: yes, 1968
Two portions of a synthetic hydroxyapatite (HA), Ca5OH(PO4)3, fully characterized by x-ray, infrared, petrographic, and chemical analyses, were heated at 1,000 C in air and steam atmospheres, respectively.
Moreno, E.C.; Gregory, T.M.; Brown, W.E.
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

THE SOLUBILITY OF CERTAIN DIFFICULTLY SOLUBLE SILVER SALTS. [PDF]

open access: yesJournal of the American Chemical Society, 1915
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openaire   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Solubility of Tannins and Preparation of Oil-Soluble Derivatives

open access: yesJournal of Oleo Science, 2018
Tannins are plant defense substances that exhibit a strong astringent taste and precipitate proteins, leading to the inhibition of protein functions; however, owing to their relatively low toxicity, tannins must be accumulated in high concentrations in cell vacuoles. Therefore, the solubility of tannins is crucial for their functions.
Tanaka, Takashi   +2 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide

open access: yesFrontiers in Pharmacology
Layered double hydroxides (LDHs) are highly effective drug delivery systems, owing to their capacity to intercalate or adsorb biomaterials, flexible structure, swelling property, high stability, good biocompatibility, and ease of synthesis.
Rehab Anwar Bakr   +11 more
doaj   +1 more source

Solubility and emulsifying activity of yam soluble protein

open access: yesJournal of Food Science and Technology, 2019
Yam soluble protein (YSP) has been reported to have many physiological activities, such as scavenging free radicals, immune activation, and anti-hypertensive activities. Protein solubility and emulsifying activity are important protein-associated functional properties for the application of proteins in food systems.
Man-Qiu Tang   +8 more
openaire   +3 more sources

Automated Solubility Screening Platform Using Computer Vision [PDF]

open access: yes, 2020
Solubility screening is an essential, routine process that is often labour intensive. Robotic platforms have been developed to automate some aspects of the manual labour involved.
Sean, Clark   +12 more
core   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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