Results 81 to 90 of about 502,416 (266)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Glycerol for improving solubility and evaluation of antimicrobial activity for natural products [PDF]
, 2016 With this study, we aimed to improve solubility and provide enhanced evaluation of antimicrobial activity with the addition of glycerol as a co-solvent with DMSO.
NC DOCKS at The University of North Carolina at Greensboro +1 more
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Thermophysical Properties of Lithium Bromide + 1, 2-Propanediol Aqueous Solutions— Solubility, Density and Viscosity [PDF]
, 2012 The solubilities, densities and viscosities of lithium bromide (LiBr) + 1, 2-propanediol (HO-CH2-CHOH-CH3) aqueous solution (mass ratio of LiBr/HO-CH2-CHOH-CH3 = 3.5, 4.5 and 5.5) were measured in the mass fraction range from 0.30 to 0.75.
Vineyard, Edward A. +2 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Analisis Tingkat Kecenderungan Pembentukan Scale pada Formula Surfaktan Berbasis Metil Ester Sulfonat untuk Aplikasi Enhanced Oil Recovery [PDF]
, 2013 Surfactant of Methyl Ester Sulfonate (MES) is used to increase the yield of oil of the old well. Decreasing of interfacial tension values is obtained after the addition of NaCl alkali concentration of 0.5 % of water injection, after that MES surfactant ...
Ningrum, Siti Kendalia
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FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Oxygen Solubility in Liquid Iron and Iron-Chromium Alloys [PDF]
, 1968 Levitation melting was used to measure the equilibrium between H2-H2o or CO-C02 gas mixtures and pure Fe or Fe-Cr alloys over the temperature range 1550 - 1750°C. The effects of thermal diffusion on the two types of gases were investigated.
Larché, Francis C. L.
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