Results 171 to 180 of about 7,812 (188)

Distribution of soluble guanylyl cyclase in rat retina

Journal of Comparative Neurology, 2006
AbstractThe nitric oxide (NO)‐cGMP pathway is implicated in modulation of visual information processing in the retina. Despite numerous functional studies of this pathway, information about the retinal distribution of the major downstream effector of NO, soluble guanylyl cyclase (sGC), is very limited.
Jin-Dong, Ding, Richard J, Weinberg
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Regulation of soluble guanylyl cyclase: looking beyond NO

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2006
neurotransmission, platelet function, skeletal muscle and vascular and nonvascular smooth muscle, and numerous other cellular functions are significantly regulated by the principal enzyme initially transducing nitric oxide (NO) signals, soluble guanylyl cyclase (sGC) ([8][1]). The better-
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YC-1, an activation inductor of soluble guanylyl cyclase

Acta Crystallographica Section C Crystal Structure Communications, 2000
The crystal structure of 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole, C(19)H(16)N(2)O(2), showed that the furan O and indazole N atoms lie on the same face of the molecule. The crystal packing consists of intermolecular hydrogen bonding, and indazole-indazole and indazole-phenyl interactions.
J, Sopková-De Oliveira Santos, V, Collot, I, Bureau, S, Rault   +3 more
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Immunolocalization of soluble guanylyl cyclase subunits in rat kidney

Histochemistry and Cell Biology, 1995
Stimulation of soluble guanylyl cyclase (SGC) by nitric oxide (NO) results in the generation of cyclic guanosine monophosphate (cGMP). We recently described expression of abundant nitric oxide synthase, the enzyme by which NO is generated from L-arginine in macula densa cells of rat kidney at the protein and mRNA level.
P, Mundel, S, Gambaryan, S, Bachmann, D, Koesling, W, Kriz   +4 more
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Measurement of cGMP and Soluble Guanylyl Cyclase Activity

Current Protocols in Toxicology, 1999
AbstractSoluble guanylyl cyclase is responsible for synthesis of guanosine 3'5'‐cyclic monophosphate. The enzyme is activated by NO, so measurement of tissue levels of cGMP and the activity of guanylyl cyclase is important in studies of NO‐cGMP signal transduction.
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Soluble Guanylyl Cyclase: The Nitric Oxide Receptor

2009
Nitric oxide (NO) plays a significant role in vasodilation, platelet aggregation, neurotransmission and many other physiological processes, and in most of these cases it works through activation of soluble guanylyl cyclase and elevation of cyclic GMP concentration.
Doris Koesling, Ari Sitaramayya
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Soluble Guanylyl Cyclase and Platelet Function^a

Annals of the New York Academy of Sciences, 1994
Büchler, Wolfgang, Ivanova, Krassimira, Wolfram, Gernot, Drummer, Christian, Heim, Jörg-Martin, Gerzer, Rupert   +5 more
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Soluble guanylyl cyclase (E.C. 4.6.1.2)

British Journal of Pharmacology, 2006
S P H Alexander, A Mathie, J A Peters
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Guanylyl Cyclase, Soluble

2007
Andreas Friebe, Doris Koesling
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Soluble guanylyl cyclase: Structure and regulation

2005
D, Koesling, A, Friebe
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