Results 171 to 180 of about 82,478 (265)
Natural Products as Modulators of ABC Transporters in Breast Cancer
Phytotherapy Research, EarlyView.ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source
, 2002 Rünker AE. Mutations in the extracellular domain of the neural cell adhesion molecule L1 impair protein trafficking in vitro and in vivo. Bielefeld (Germany): Bielefeld University; 2002.Das neurale Zelladhäsionsmolekül L1 ist ein Mitglied der ...
Rünker, Annette E.
core
The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis
Phytotherapy Research, EarlyView.ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang +7 more
wiley +1 more source
Responsive Materials, EarlyView.Machine learning provides a unifying framework to connect structure, fluorescence properties, and applications of carbon‐based quantum dots. This review highlights how data‐driven strategies enable fluorescence regulation, reveal underlying mechanisms, and accelerate the rational design of functional carbon dots.
Liangfeng Chen +8 more
wiley +1 more source
Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges
The Chemical Record, EarlyView.Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley +1 more source
Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping
The Chemical Record, EarlyView.Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato +3 more
wiley +1 more source
Prostate cancer diagnosis using plasma extracellular vesicles isolated via aqueous two‐phase systems
VIEW, EarlyView.Abstract Prostate cancer (PCa) is the second most prevalent cancer in men, with early detection and precise staging remaining critical for improving outcomes. While PSA tests and biopsies are widely used, they suffer from low specificity and often lead to unnecessary procedures.
Yongmin Kwon +6 more
wiley +1 more source
Determination of exosomal PD-L1 in patients with advanced neoplasms
Ilustraciones, gráficosEl campo de los biomarcadores en cáncer constituye una extensa área de investigación aún en fase de exploración. Muchas de las complicaciones asociadas con el cáncer derivan de la carencia de un diagnóstico expedito y las ...
Duque Arbelaez, Jorge Eduardo
core +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
IFN-γ upregulates membranous and soluble PD-L1 in mesothelioma cells: potential implications for the clinical response to PD-1/PD-L1 blockade [PDF]
Cellular & Molecular Immunology, 2019 Pistillo M. P. +9 more
openaire +2 more sources