Results 71 to 80 of about 4,013,036 (260)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Protein Expr. Purif.

, 2006
A novel artificial chaperone system using a combination of interactions between the unfolded protein, a detergent and a chromatographic column packed with immobilized P-cyclodextrin (P-CD) polymer coupled to an agarose gel, was introduced to refold ...
Su, ZG, Venkataramana, M, Sanyal, S, Janson, JC, Li, JJ   +4 more
core   +1 more source

Soluble Flt-1 and PlGF: new markers of early pregnancy loss? [PDF]

, 2011
Recent data have indicated a relationship between placental oxygen and angiogenic protein levels in the first trimester of normal pregnancies. Our objective was to investigate if maternal serum levels of angiogenic factors Soluble vascular endothelial ...
Michelle Swer, Muttukrishna, S, Suri, S, Jurkovic, Davor, Jamil, Amna, Swer, Michelle, Suri, Sangeeta, Sangeeta Suri, Jauniaux, E, Gangooly, Subrata, Gangooly, S, Calleja-Agius, Jean, Jamil, A, Amna Jamil, Ludlow, H, Muttukrishna, Shanthi, Jurkovic, D, Helen Ludlow, Davor Jurkovic, Calleja-Agius, J, Eric Jauniaux, Subrata Gangooly, Swer, M, Jean Calleja-Agius, Jauniaux, Eric R.M., Ludlow, Helen, Shanthi Muttukrishna, Jamil Amna, Suri Sangeeta, Calleja-Agius Jean, Muttukrishna Shanthi, Gangooly Subrata, Jauniaux, Eric, Swer Michelle, Jurkovic Davor, Ludlow Helen, Jauniaux Eric   +36 more
core   +2 more sources

Editorial: Protein Solubility and Aggregation in Bacteria [PDF]

Frontiers in Microbiology, 2016
For many years, the aggregation of proteins and polypeptides remained a neglected area of protein chemistry. It was only with the discovery that the insoluble deposits found in the organs and tissues of patients suffering from different diseases were enriched in a single, but different polypeptide, that the interest in understanding how and why these ...
openaire   +3 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Translational and rotational motions of albumin sensed by a non-covalent associated porphyrin under physiological and acidic conditions: a fluorescence correlation spectroscopy and time resolved anisotropy study. [PDF]

, 2008
The interaction between a free-base, anionic water-soluble porphyrin, TSPP, and the drug carrier protein, bovine serum albumin (BSA) has been studied by time-resolved fluorescence anisotropy (TRFA) and fluorescence correlation spectroscopy (FCS) at two ...
Costa, S.M., Hoek, A., van, Borst, J.W., Visser, A.J.W.G., Andrade, S.M.   +4 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies

, 2023
Tau protein aggregates in several neurodegenerative disorders, referred to as tauopathies. The tau isoforms observed in post mortem human brain aggregates is used to classify tauopathies.
Mark H. Rider, Balty, Clémence, Nathalie Kyalu Ngoie Zola, Nicolas D. G. Huyghe, Kienlen-Campard, Pascal, Emilien Boyer, Manuel Johanns, Pascal Kienlen-Campard, Rider, Mark H., Didier Vertommen, Vanparys, Axelle, Bernard J. Hanseeuw, Sébastien Pyr dit Ruys, Boyer, Emilien, Herinckx, Gaëtan, Clémence Balty, Vertommen, Didier, Huyghe, Nicolas, Johanns, Manuel, Axelle A. T. Vanparys, Kyalu Ngoie Zola, Nathalie, Pyr dit Ruys, Sébastien, Gaëtan Herinckx, Hanseeuw, Bernard   +23 more
core   +1 more source

Rapid and Differential Diagnosis of Sepsis Stages Using an Advanced 3D Plasmonic Bimetallic Alloy Nanoarchitecture‐Based SERS Biosensor Combined with Machine Learning for Multiple Analyte Identification

Advanced Science
Rapid and accurate differential diagnosis of infections, sepsis, and septic shock is essential for preventing unnecessary antibiotic overuse and improving the chance of patient survival.
Woo Hyun Kim, Sungwoo Lee, Myeong Jin Jeon, Kwon Jun Lee, Jong‐Hak Park, Dae Won Park, Sungho Park, Sang Jun Sim   +7 more
doaj   +1 more source

Study on the rooting promotion of chrysanthemum cuttings by Massilia consociata KC 009

Frontiers in Plant Science
Continuous cropping reduces the rooting rate and quality of chrysanthemum cuttings, negatively impacting the development of the chrysanthemum industry.
Chunmei Lu, Haotian Dong, Yu Jiao, Murad Muhammad, Murad Muhammad, Yuanchun Yang, Jing Zhang, Rui Liu, Yanru Cao   +8 more
doaj   +1 more source