Results 101 to 110 of about 402 (126)

Soluble ST2: A complex and diverse role in several diseases

Clinica Chimica Acta, 2020
The Suppression of Tumorigenicity 2 protein (ST2) is a member of the interleukin (IL) 1 receptor family with transmembrane (ST2L) and soluble (sST2) isoforms that are (over)expressed in several cells in different conditions and following various triggers (e.g. inflammation, stress).
Evgenija Homsak, Damien Gruson
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Magnitude of Soluble ST2 as a Novel Biomarker for Acute Aortic Dissection [PDF]

Circulation, 2018
Background: Misdiagnosis of acute aortic dissection (AAD) can lead to significant morbidity and death. Soluble ST2 (sST2) is a cardiovascular injury–related biomarker. The extent to which sST2 is elevated in AAD and whether sST2 can discriminate AAD from other causes of sudden-onset severe chest pain are unknown.
Hai Gao, Yuan Wang, Pei Gao
exaly   +3 more sources

Soluble ST2 in Ventricular Dysfunction

2015
Heart failure is a commonly encountered condition associated with increased morbidity, mortality, and healthcare cost. For years, its management has been strongly influenced by the use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide biomarkers. In some cases, this approach does not always identify patients with heart failure
Silvia, Lupu, Lucia, Agoston-Coldea
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Soluble ST2 and Galectin-3 in Heart Failure

Clinics in Laboratory Medicine, 2014
Circulating biomarkers that directly reflect disease progression, hemodynamics, and ventricular remodeling at a molecular level are critical to risk stratification in heart failure (HF), affording unique insights into pathophysiology not fully captured by traditional risk markers.
Ravi V, Shah, James L, Januzzi
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Soluble ST2 and Soluble Markers of Fibrosis: Emerging Roles for Prognosis and Guiding Therapy

Current Cardiology Reports, 2020
Biomarkers of cardiac fibrosis closely track the disease state that gives rise to heart failure. The purpose of this review is to highlight recent data on the use of soluble ST2, galectin-3, and procollagen, three markers of cardiac fibrosis, for aiding with prognostication, and to explore the use of these biomarkers for guiding therapy.Soluble ST2 ...
Justin, Sharim, Lori B, Daniels
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Soluble ST2 as a prognostic marker in community-acquired pneumonia

Journal of Infection, 2015
Community-acquired pneumonia (CAP) is associated with high mortality when initial treatment fails. Early identification of these patients allows physicians to modify treatments earlier, increasing survival.Ninety-one hospitalized patients with CAP were studied.
Masato, Watanabe, Hajime, Takizawa, Masaki, Tamura, Akira, Nakajima, Daisuke, Kurai, Haruyuki, Ishii, Saori, Takata, Keitaro, Nakamoto, Erei, Sohara, Koujirou, Honda, Masuo, Nakamura, Toshiya, Inui, Hiroo, Wada, Hajime, Goto   +13 more
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Soluble ST2 Serum Concentration and Renal Function in Heart Failure

Journal of Cardiac Failure, 2013
Soluble ST2 (sST2) provides important prognostic information in patients with heart failure (HF). How sST2 serum concentration is related to renal function is uncertain. We evaluated the association between sST2 and renal function and compared its prognostic value in HF patients with renal insufficiency.Patients (n = 879; median age 70.4 years; 71.8 ...
Bayes-Genis, A, Zamora, E, de Antonio, M, Galan, A, Vila, J, Urrutia, A, Diez, C, Coll, R, Altimir, S, Lupon, L   +9 more
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Determinants and implications of elevated soluble ST2 levels in heart failure

International Journal of Cardiology, 2014
To the Editor:Recently several new putative cardiac biomarkers detectable inthe peripheral circulation have been described, including moleculessuch as soluble ST2 and galectin-3 [1]. The ST2 gene encodes theIL1RL-1 receptor which is expressed in many tissues and cell types,andpreferentiallybindsinterleukin-33(IL33).InthecontextofHF,pre-vious studies ...
Micha Maeder, Vanessa Van Empel, Justin Mariani   +2 more
exaly   +4 more sources

Association of soluble ST2 with functional capacity in outpatients with heart failure

Herz, 2017
Biomarkers play an important role in the risk stratification of patients with heart failure (HF). Recent studies have shown that soluble suppression of tumorigenicity 2 (sST2), a member of the interleukin 1 receptor family, is associated with disease prognosis in acute and chronic HF.
Yucel, O., Gul, I, Zararsiz, A., Demirpence, O., Yucel, H., Cinar, Z., Zorlu, A., Yilmaz, M. B.   +7 more
openaire   +4 more sources

Long-term stability of soluble ST2 in frozen plasma samples

Clinical Biochemistry, 2010
The aim of this study was to investigate the long-term in vitro stability of soluble ST2 (sST2).EDTA plasma samples were drawn from 15 individuals with various diseases. The Presage ST2 assay was used for measurement of sST2 concentrations directly after blood collection and after storing plasma samples for 18 months at -20 degrees C and -80 degrees C.
Benjamin, Dieplinger, Margot, Egger, Werner, Poelz, Meinhard, Haltmayer, Thomas, Mueller   +4 more
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