The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity
The Journal of Physiology, EarlyView.Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas +5 more
wiley +1 more source
ANALISIS KADAR GROWTH DIFFERENTIATION FACTOR-15, GALEKTIN-3, SOLUBLE SUPPRESSION OF TUMORIGENICITY-2 SERUM DENGAN KEJADIAN DISFUNGSI SISTOLIK DINI VENTRIKEL KANAN PADA PENDERITA HIPERTENSI ARTERI PULMONAL [PDF]
ABSTRAK Analisis Kadar Growth Differentiation Factor-15, Galektin-3, Soluble Suppression Of Tumorigenicity-2 Serum Dengan Kejadian Disfungsi Sistolik Dini Ventrikel Kanan Pada Penderita Hipertensi Arteri Pulmonal Mefri Yanni Hipertensi arteri ...
Yanni, Mefri
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International Journal of Cancer, Volume 159, Issue 8, Page 1974-1989, 15 October 2026.Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger +13 more
wiley +1 more source
Association of soluble suppression of tumorigenicity 2 protein with new-onset atrial fibrillation in patients with acute ST-segment elevation myocardial infarction undergoing primary PCI. [PDF]
Front Cardiovasc Med, 2023 Zhao TT +4 more
europepmc +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.ABSTRACT Helicobacter pylori infection is characterized by chronic gastric inflammation driven by persistent activation of innate immune signalling pathways. Outer membrane vesicles (OMVs) released by H. pylori are important mediators of host–pathogen interactions. Although several mechanisms of OMV internalization have been described, how specific OMV‐
Mariaignacia Rubilar +6 more
wiley +1 more source
Biomarkers for Predicting the Occurrence and Progression of Atrial Fibrillation: Soluble Suppression of Tumorigenicity 2 Protein and Tissue Inhibitor of Matrix Metalloproteinase-1. [PDF]
Int J Clin Pract, 2022 Sun WP, Du X, Chen JJ.
europepmc +1 more source
MedComm, Volume 7, Issue 10, October 2026.• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo +4 more
wiley +1 more source
SUPPRESSION OF PROPERTIES ASSOCIATED WITH MALIGNANCY IN MURINE MELANOMA-MELANOCYTE HYBRID-CELLS [PDF]
, 1992 J Greetham +7 more
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Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies
MedComm, Volume 7, Issue 10, October 2026.The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao +7 more
wiley +1 more source
Diagnostic and prognostic value of serum soluble suppression of tumorigenicity-2 in heart failure with preserved ejection fraction: A systematic review and meta-analysis. [PDF]
Front Cardiovasc Med, 2022 Shi Y +6 more
europepmc +1 more source