Results 201 to 210 of about 20,000 (219)
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Journal of Leukocyte Biology
Abstract The prognostic significance of soluble immune checkpoint molecule TIM-3 and its ligands in the plasma has been illustrated in various solid tumors, but such study in newly diagnosed acute myeloid leukemia (AML) remains absent.
Qian Jiang +2 more
exaly +3 more sources
Abstract The prognostic significance of soluble immune checkpoint molecule TIM-3 and its ligands in the plasma has been illustrated in various solid tumors, but such study in newly diagnosed acute myeloid leukemia (AML) remains absent.
Qian Jiang +2 more
exaly +3 more sources
Human Immunology
Preeclampsia (PE) is characterized by immune dysfunction, including altered expression levels of multiple immune checkpoints (ICs), which are essential for inducing immune tolerance during pregnancy. While the pivotal role of ICs in PE is well-established, a limited understanding remains of the changes in their various forms, particularly in their ...
Leili Aghebati-Maleki +2 more
exaly +3 more sources
Preeclampsia (PE) is characterized by immune dysfunction, including altered expression levels of multiple immune checkpoints (ICs), which are essential for inducing immune tolerance during pregnancy. While the pivotal role of ICs in PE is well-established, a limited understanding remains of the changes in their various forms, particularly in their ...
Leili Aghebati-Maleki +2 more
exaly +3 more sources
The Diagnostic Value of Soluble TIM-3 in Oral Squamous Cell Carcinoma
Future Oncology, 2022Objective: To evaluate the soluble TIM-3 (sTIM-3) expression level in oral squamous cell carcinoma (OSCC) and determine its clinical diagnostic potential. Methods: The sTIM-3 and squamous cell carcinoma antigen (SCCAg) levels of 199 OSCC patients and 107 healthy individuals were assessed using an enzyme-linked immunosorbent assay and their individual ...
Kairui Lu +4 more
openaire +2 more sources
Alcohol, 2022
The involvement of immune checkpoint regulators (ICs) in alcohol-associated liver diseases (ALDs) is still largely unknown. Here, we analyzed the levels of 16 soluble ICs (sICs) in male patients with ALD to determine their clinical significance. The 16 sICs were measured using a luminex-based multiplex assay in 115 patients with ALD and 47 healthy ...
Ailyn Fadriquela +4 more
openaire +2 more sources
The involvement of immune checkpoint regulators (ICs) in alcohol-associated liver diseases (ALDs) is still largely unknown. Here, we analyzed the levels of 16 soluble ICs (sICs) in male patients with ALD to determine their clinical significance. The 16 sICs were measured using a luminex-based multiplex assay in 115 patients with ALD and 47 healthy ...
Ailyn Fadriquela +4 more
openaire +2 more sources
Characterization of human soluble Tim-3 and its role in HIV infection (VIR1P.1002)
The Journal of Immunology, 2014Abstract Chronic Human Immunodeficiency Virus Type-1 (HIV) infection results in a loss of HIV-specific CD8+ T cell effector function, termed “exhaustion”, which is mediated, in-part, by the co-inhibitory receptor T-cell immunoglobulin mucin domain-containing protein 3 (Tim-3). Like many other receptors, a soluble form of this protein has
Kiera Clayton +6 more
openaire +1 more source
The Journal of Immunology, 2015
Abstract Chronic HIV infection results in a loss of HIV-specific CD8+ T cell effector function, termed “exhaustion”, mediated, in part, by the co-inhibitory receptor T cell immunoglobulin mucin domain-3 (Tim-3). Like many other receptors, a soluble form of this protein has been described in human blood plasma.
Kiera Clayton +11 more
openaire +1 more source
Abstract Chronic HIV infection results in a loss of HIV-specific CD8+ T cell effector function, termed “exhaustion”, mediated, in part, by the co-inhibitory receptor T cell immunoglobulin mucin domain-3 (Tim-3). Like many other receptors, a soluble form of this protein has been described in human blood plasma.
Kiera Clayton +11 more
openaire +1 more source
Serum soluble TIM-3 levels are increased in patients with diffuse cutaneous systemic sclerosis
Journal of Dermatological Science, 2017Miki Chiba +4 more
openaire +1 more source