Results 111 to 120 of about 1,781,718 (260)

Computational backbone design enables soluble engineering of transferrin receptor apical domain

, 2020
Supply of iron into human cells is achieved by iron carrier protein transferrin and its receptor that upon complex formation get internalized by endocytosis.
Dick J. Sjöström, Sinisa Bjelic, Oberdorfer, Gustav,, Sjöström, Dick J.,, Bjelic, Sinisa,, Berger, Sarah A.,, Gustav Oberdorfer, Sarah A. Berger   +7 more
core   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

The FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini, Konstantinos Poalas, Margaux Versapuech, Clarisse Berlioz‐Torrent, Katy Janvier   +4 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Soluble Transferrin Receptor as Iron Deficiency Biomarker: Impact on Exercise Capacity in Heart Failure Patients. [PDF]

J Pers Med, 2023
Ras-Jiménez MDM, Ramos-Polo R, Francesch Manzano J, Corbella Santano M, Morillas Climent H, Jose-Bazán N, Jiménez-Marrero S, Garcimartin Cerezo P, Yun Viladomat S, Moliner Borja P, Torres Cardús B, Verdú-Rotellar JM, Diez-López C, González-Costello J, García-Romero E, de Frutos Seminario F, Triguero-Llonch L, Enjuanes Grau C, Tajes Orduña M, Comin-Colet J.   +19 more
europepmc   +1 more source

Transferrin receptor 2 is crucial for iron sensing in human hepatocytes

, 2010
Hepcidin expression in vivo is regulated in proportion to iron status (i.e., increased by iron loading and decreased in iron deficiency). However, in vitro studies with hepatoma cell lines often show an inverse relationship between iron status and ...
Hughes, R.D., Rapisarda, C., Evans, R.W., Dhawan, A., Farnaud, S., Puppi, J., Sharp, P.A.   +6 more
core  

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Soluble transferrin receptor in Aboriginal children with a high prevalence of iron deficiency and infection

, 2004
OBJECTIVES: Aboriginal children in tropical Australia have a high prevalence of both iron deficiency and acute infections, making it difficult to differentiate their relative contributions to anaemia.
McNeil, Y., Brewster, D.R., Ritchie, B.
core   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Reticulocyte transferrin receptor (TfR) expression and contribution to soluble TfR levels

Haematologica, 2001
BACKGROUND AND OBJECTIVES: Transferrin receptor (TfR) expression in erythroid cells is regulated by a number of factors, including iron status and erythropoietin (Epo) stimulation.
S R'zik, M Loo, Y Beguin
doaj  

Potential Impact of Large‐Scale Food Fortification in Ethiopia: Coverage and Knowledge of Fortifiable Foods

Maternal &Child Nutrition, EarlyView.
Coverage of fortifiable oil, salt, and wheat flour by wealth quintiles. ABSTRACT Large‐scale food fortification (LSFF) is an effective public health measure because it may reach a large number of populations at risk using current food delivery systems.
Aregash Samuel, Ramadhani Noor, Nahom Tefera, Alemayehu Hussien, Genet Gebremedhin, Mduduzi Mbuya, Endale Amare, Meseret Woldeyohannes, Getinet Fikresilassie, Meron Girma, Alemnesh Petros, Anbissa Muleta, Bedasa Tessema, Feyissa Chala, Kaleab Baye, Arnaud Laillou, Tesfaye Chuko, Getachew Tollera, Mesay Hailu, Stanley Chitekwe, Masresha Tessema   +20 more
wiley   +1 more source