Association between soluble transferrin receptor and systolic hypertension in adults: National Health and Nutrition Examination Survey (2007-2010 and 2015-2018). [PDF]
Wang H, Qi Q, Song S, Zhang D, Feng L.
europepmc +1 more source
The transferrin receptor: Role in health and disease
The transferrin receptor is a membrane glycoprotein whose only clearly defined function is to mediate cellular uptake of iron from a plasma glycoprotein, transferrin.
Ponka, P, Lok, CN
core +1 more source
Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi +12 more
wiley +1 more source
Chelator-facilitated removal of iron from transferrin: Relevance to combined chelation therapy [PDF]
Current iron chelation therapy consists primarily of DFO (desferrioxamine), which has to be administered via intravenous infusion, together with deferiprone and deferasirox, which are orally-active chelators.
Evans, PJ +3 more
core +1 more source
Assessment of WHO 07/202 reference material and human serum pools for commutability and for the potential to reduce variability among soluble transferrin receptor assays. [PDF]
Lyle AN +6 more
europepmc +1 more source
This study reveals that lactational HS suppresses Sirt3 activity, leading to hyperacetylation of the complex I subunit NDUFS1, and excessive mitochondrial ROS production, whereas BAI, a nature food‐derived bioactive compound, alleviates lactational HS‐induced hepatic mitochondrial injury by activating the Sirt3–NDUFS1 axis to deacetylate mitochondrial ...
Jingzheng Li +3 more
wiley +1 more source
Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno +3 more
wiley +1 more source
Impact of inflammation on anemia in children: a cross-sectional study
Introduction The association of inflammation and iron deficiency could be related to up to 40% of anemia in young children. Objective To describe the anemia and iron deficiency in children and verify possible associations with dietary practices ...
Luiz Felipe de Paiva Lourenção +5 more
doaj +1 more source
: In hereditary hemolytic anemia (HHA), soluble transferrin receptor (sTfR) reflects erythropoietic activity, whereas in iron deficiency anemia, it indicates iron-restricted hematopoiesis.
Geoffrey Z. L. Kuppens +11 more
doaj +1 more source
Stages of chronic kidney disease and soluble Transferrin Receptor (sTfR), Ferritin, ratio [PDF]
Objective: To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic kidney disease.Methods: This case-control study was conducted at the Aga Khan University Hospital and the Jinnah Postgraduate Medical Centre ...
Fatima, Syeda Sadia +4 more
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