Results 131 to 140 of about 1,781,718 (260)

The transferrin receptor: Role in health and disease

open access: yes, 1999
The transferrin receptor is a membrane glycoprotein whose only clearly defined function is to mediate cellular uptake of iron from a plasma glycoprotein, transferrin.
Ponka, P, Lok, CN
core   +1 more source

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi   +12 more
wiley   +1 more source

Chelator-facilitated removal of iron from transferrin: Relevance to combined chelation therapy [PDF]

open access: yes, 2008
Current iron chelation therapy consists primarily of DFO (desferrioxamine), which has to be administered via intravenous infusion, together with deferiprone and deferasirox, which are orally-active chelators.
Evans, PJ   +3 more
core   +1 more source

Baicalin Alleviates Lactational Heat‐Stress‐Induced Hepatic Mitochondrial Dysfunction via Sirt3‐Dependent Deacetylation of NDUFS1

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
This study reveals that lactational HS suppresses Sirt3 activity, leading to hyperacetylation of the complex I subunit NDUFS1, and excessive mitochondrial ROS production, whereas BAI, a nature food‐derived bioactive compound, alleviates lactational HS‐induced hepatic mitochondrial injury by activating the Sirt3–NDUFS1 axis to deacetylate mitochondrial ...
Jingzheng Li   +3 more
wiley   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno   +3 more
wiley   +1 more source

Impact of inflammation on anemia in children: a cross-sectional study

open access: yesBMC Pediatrics
Introduction The association of inflammation and iron deficiency could be related to up to 40% of anemia in young children. Objective To describe the anemia and iron deficiency in children and verify possible associations with dietary practices ...
Luiz Felipe de Paiva Lourenção   +5 more
doaj   +1 more source

Erythroid-derived extracellular vesicles and interplay with soluble transferrin receptor in hereditary hemolytic anemias

open access: yesBlood Red Cells & Iron
: In hereditary hemolytic anemia (HHA), soluble transferrin receptor (sTfR) reflects erythropoietic activity, whereas in iron deficiency anemia, it indicates iron-restricted hematopoiesis.
Geoffrey Z. L. Kuppens   +11 more
doaj   +1 more source

Stages of chronic kidney disease and soluble Transferrin Receptor (sTfR), Ferritin, ratio [PDF]

open access: yes, 2017
Objective: To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic kidney disease.Methods: This case-control study was conducted at the Aga Khan University Hospital and the Jinnah Postgraduate Medical Centre ...
Fatima, Syeda Sadia   +4 more
core  

Home - About - Disclaimer - Privacy