Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy
MedComm, Volume 7, Issue 11, November 2026.Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu +8 more
wiley +1 more source
Response to "Relationship between soluble transferrin receptor and type 2 diabetes mellitus: A meta-analysis". [PDF]
J Diabetes Investig, 2021 Liu J.
europepmc +1 more source
British Journal of Pharmacology, Volume 183, Issue 21, Page 6329-6351, November 2026.Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu +14 more
wiley +1 more source
Biology and receptor interactions of P97 and the transferrin receptors
, 2002 Melanotransferrin, or p97, is an iron binding protein that is expressed as both a glycosylphosphatidylinositol-anchored form and as a soluble form. While the anchored form internalizes iron, the function of the soluble form is still unknown.
Walker, Brandie Laurel
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Soluble Transferrin Receptor during infancy and reference intervals for the Roche Cobas platform. [PDF]
Int J Lab Hematol, 2021 Larsson SM +7 more
europepmc +1 more source
Natural Product‐Induced Ferroptosis to Overcome Therapy Resistance in Aggressive Cancers
ChemMedChem, Volume 21, Issue 20, 28 October 2026.Natural products trigger ferroptosis through iron overload, glutathione depletion, glutathione peroxidase 4 inhibition, and reactive oxygen species accumulation, selectively targeting aggressive, and drug‐resistant cancers. Polyphenols, alkaloids and terpenoids emerge as promising multi‐target agents to overcome therapy resistance and improve future ...
Giorgio Antoniolli
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Increased Serum Soluble Transferrin Receptor Levels Were Associated With High Prevalence of Cardiovascular Diseases: Insights From the National Health and Nutrition Examination Survey 2017-2018. [PDF]
Front Cell Dev Biol, 2022 Zhu S +7 more
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International Journal of Cancer, Volume 159, Issue 8, Page 1974-1989, 15 October 2026.Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger +13 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, Volume 600, Issue 20, Page 3051-3072, October 2026.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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Prevalence of postpartum anaemia and iron deficiency by serum ferritin, soluble transferrin receptor and total body iron, and associations with ethnicity and clinical factors: a Norwegian population-based cohort study. [PDF]
J Nutr Sci, 2022 Næss-Andresen ML +4 more
europepmc +1 more source