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Tohoku Journal of Experimental Medicine, 2004 We aimed to evaluate the diagnostic values of soluble transferrin receptor (sTfR) concentration, transferrin-ferritin index (soluble transferrin receptor concentration/log ferritin), ferritin levels and other related parameters in geriatric patients with anemia of chronic disease (ACD) and iron deficiency (IDA).
Bülent Saka +2 more
exaly +5 more sources
Biological and clinical aspects of soluble transferrin receptor
Critical Reviews in Clinical Laboratory Sciences, 2010 Soluble transferrin receptor (sTfR), one of the main regulators of cellular iron homeostasis, is the truncated form of the tissue receptor that is encoded by the human TfR gene (chromosome 3). Serum sTfR levels are determined to detect iron deficiency (ID) in inflammatory states and in anemia of chronic disease (ACD) and to monitor the efficiency of ...
Marijn M Speeckaert +2 more
exaly +4 more sources
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International Journal of Laboratory Hematology, 2007
SummaryTransferrin receptor is a transmembrane protein that mediates iron transport from blood into cells. The extracellular part of this receptor circulates in blood as soluble transferrin receptor (sTfR) and the immunological determination of this parameter is widely used in clinical practice.
A E, Kogan +4 more
exaly +3 more sources
SummaryTransferrin receptor is a transmembrane protein that mediates iron transport from blood into cells. The extracellular part of this receptor circulates in blood as soluble transferrin receptor (sTfR) and the immunological determination of this parameter is widely used in clinical practice.
A E, Kogan +4 more
exaly +3 more sources
Soluble transferrin receptor in complicated anemia
Clinica Chimica Acta, 2014Determination of serum soluble transferrin receptor (sTfR) has been proposed to identify iron-deficiency anemia (IDA) in patients affected by concurrent inflammatory disease that may spuriously increase ferritin concentration. The aim of this study was to critically review the available literature to assess the diagnostic efficacy of sTfR in ...
F. Braga +3 more
openaire +2 more sources
Relationship between Soluble Transferrin Receptors in Serum and Membrane-Bound Transferrin Receptors
Acta Haematologica, 1998The expression of transferrin receptors on the cell membrane of erythroblasts was analysed with flow cytometry in patients with different forms of anaemia. At the same time the concentration of soluble transferrin receptors (sTfRs) was analysed in serum. It was shown that only in iron deficiency a high concentration of sTfRs in serum could be explained
Kuiper -Kramer, PA +5 more
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Soluble transferrin receptor for the evaluation of erythropoiesis and iron status [PDF]
Clinica Chimica Acta, 2003 Iron transport in the plasma is carried out by transferrin, which donates iron to cells through its interaction with a specific membrane receptor, the transferrin receptor (TfR). A soluble form of the TfR (sTfR) has been identified in animal and human serum. Soluble TfR is a truncated monomer of tissue receptor, lacking its first 100 amino acids, which
Yves Beguin
exaly +4 more sources
World Journal of Pediatrics, 2009
Recent studies showing an improved diagnosis of iron deficiency (ID) with soluble transferrin receptor (sTfR) and sTfR-ferritin index did not take into account the age-dependency of sTfR and ferritin. Moreover, there is a paucity of data on pediatric reference intervals for sTfR and sTfR-ferritin index.A study cohort of 436 apparently healthy children ...
Ooi, Cara Lianne +4 more
openaire +3 more sources
Recent studies showing an improved diagnosis of iron deficiency (ID) with soluble transferrin receptor (sTfR) and sTfR-ferritin index did not take into account the age-dependency of sTfR and ferritin. Moreover, there is a paucity of data on pediatric reference intervals for sTfR and sTfR-ferritin index.A study cohort of 436 apparently healthy children ...
Ooi, Cara Lianne +4 more
openaire +3 more sources
Obstetrics & Gynecology, 2002
To assess the impact of pregnancy and lactation on iron status and erythropoiesis as measured by the soluble transferrin receptor (sTfR).We recruited women in early pregnancy to be followed for 2 years. We determined sTfR and sTfR/serum ferritin (sTfR/Fer) during puerperium (n = 77), lactation (n = 111), and postlactation (n = 57), with comparison to ...
Agneta, Akesson +4 more
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To assess the impact of pregnancy and lactation on iron status and erythropoiesis as measured by the soluble transferrin receptor (sTfR).We recruited women in early pregnancy to be followed for 2 years. We determined sTfR and sTfR/serum ferritin (sTfR/Fer) during puerperium (n = 77), lactation (n = 111), and postlactation (n = 57), with comparison to ...
Agneta, Akesson +4 more
openaire +2 more sources
Measurement of soluble transferrin receptor by immunoturbidimetry and immunonephelometry
Clinical Biochemistry, 2000To evaluate and compare two new commercially available immunoturbidimetric and immunonephelometric assays for measuring soluble transferrin receptor (sTfR) in serum. To adapt the immunonephelometric assay to an automated chemistry analyzer.Total imprecisions and detection limits were calculated and compared.
Cotton, Frédéric +2 more
openaire +3 more sources
Immunological study of complex formation between soluble transferrin receptor and transferrin [PDF]
American Journal of Hematology, 2005 Transferrin receptor (TfR) is a dimeric transmembrane protein that provides iron transport from plasma to cells by binding and internalization of iron-loaded transferrin (Tf). Soluble transferrin receptor (sTfR) is an extracellular part of the TfR molecule that is truncated from the cell surface and released into the blood stream.
A, Kogan +5 more
exaly +3 more sources