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The assessment of serum soluble transferrin receptor in alcoholics
Clinical and Experimental Medicine, 2009The consumption of large amounts of alcohol disturbs body iron metabolism and leads to increase of body iron stores and may cause various hematologic changes. Both, iron overload and iron depletion could have effect on the metabolic, transit and storage pools.
Bogdan, Cylwik +4 more
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Evaluation of kits for measurement of the soluble transferrin receptor
Scandinavian Journal of Clinical and Laboratory Investigation, 1999Three commercially available kits for determination of the soluble serum transferrin receptor (sTfR), R&D Systems, UK, Ramco Laboratories, USA and Orion, Finland were compared with respect to practicability, comparability and ability to discriminate between iron deficient and non-iron deficient subjects.
A, Akesson, P, Bjellerup, M, Vahter
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Transferrin Receptor in Tissue and Serum: Updated Clinical Significance of Soluble Receptor
International Journal of Hematology, 2002The transferrin receptor is an essential component of cellular uptake of iron, and it binds to serum transferrin. Recently, 2 different types of transferrin receptors have been recognized: transferrin receptor (TfR or transferrin receptor 1) and transferrin receptor 2.
Junji Kato
exaly +3 more sources
Clinica Chimica Acta, 2005
The measurement of soluble transferrin receptor (sTfR) has been proposed as a valuable marker of erythropoietic activity and iron status. However, the possibility that mutations in HFE and/or transferrin genes have a direct effect on this parameter has not been sufficiently investigated. The present report addresses this point in the general population.
Nuria Aranda +2 more
exaly +3 more sources
The measurement of soluble transferrin receptor (sTfR) has been proposed as a valuable marker of erythropoietic activity and iron status. However, the possibility that mutations in HFE and/or transferrin genes have a direct effect on this parameter has not been sufficiently investigated. The present report addresses this point in the general population.
Nuria Aranda +2 more
exaly +3 more sources
The soluble transferrin receptor in dysplastic erythropoiesis in myelodysplastic syndrome
European Journal of Haematology, 2007Abstract Objectives: In individuals without iron deficiency, the soluble transferrin receptor (sTfR) directly reflects the erythropoietic activity. This study investigated sTfR concentrations in ineffective, dysplastic erythropoiesis in myelodysplastic syndrome (MDS).
Georgia, Metzgeroth +6 more
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Production of soluble transferrin receptor by K562 erythroleukaemia cells
British Journal of Haematology, 1991Summary. The present study was undertaken to examine the production of soluble transferrin receptor by K562 erythroleukaemia cells under controlled experimental conditions. The concentrations of soluble and cellular transferrin receptor were measured by immunoassay employing monoclonal antibodies.
R D, Baynes, Y J, Shih, J D, Cook
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Soluble Transferrin Receptor and Iron Status in Elderly Patients
Wiener Medizinische Wochenschrift, 2003The measurement of soluble transferrin receptor (sTfR) has been proposed as a novel approach to the diagnosis of iron deficiency, especially in anaemia of chronic diseases (ACD). Our aim was to study the utility of sTfR under 'everyday conditions' as seen in a geriatric hospital in the following groups of patients: First, in a pilot group of 99 ...
Franz, Böhmer +2 more
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Acta Paediatrica, 2000
Soluble transferrin receptor (sTfR) is a new diagnostic tool for determining iron status and erythropoietic activity. The increased concentrations of sTfR in patients with iron deficiency reflect the hyperplasia of erythroid precursors. The objective of this study was to evaluate sTfR and sTfR/ log ferritin index (sTfR‐F) values in healthy children (n =
H, Dimitriou +5 more
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Soluble transferrin receptor (sTfR) is a new diagnostic tool for determining iron status and erythropoietic activity. The increased concentrations of sTfR in patients with iron deficiency reflect the hyperplasia of erythroid precursors. The objective of this study was to evaluate sTfR and sTfR/ log ferritin index (sTfR‐F) values in healthy children (n =
H, Dimitriou +5 more
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The Medical journal of Malaysia, 2008
Anaemia of chronic disease (ACD) is a frequent complication of rheumatoid arthritis (RA). A diagnostic difficulty in RA is the distinction between iron deficiency anaemia (IDA) and ACD. The aim of our study was to evaluate the usefulness of serum soluble transferrin receptor (sTfR) and sTfR/log ferritin (TfR-F) index to diagnose iron deficiency in RA ...
S, Pavai, S, Jayaranee, S, Sargunan
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Anaemia of chronic disease (ACD) is a frequent complication of rheumatoid arthritis (RA). A diagnostic difficulty in RA is the distinction between iron deficiency anaemia (IDA) and ACD. The aim of our study was to evaluate the usefulness of serum soluble transferrin receptor (sTfR) and sTfR/log ferritin (TfR-F) index to diagnose iron deficiency in RA ...
S, Pavai, S, Jayaranee, S, Sargunan
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Soluble transferrin receptor in beta-thalassaemia
The Lancet, 1993P, Musto +5 more
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