Results 121 to 130 of about 7,358,591 (308)

Bridging the Knowledge Gap in Harmaline’s Pharmacological Properties: A Focus on Thermodynamics and Kinetics

open access: yesPharmaceutics
Background/Objectives: Advancing information on the key physicochemical properties of biologically active substances enables the development of formulations with reduced dosing, lower toxicity, and minimal adverse effects.
Tatyana Volkova   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Development and Testing of ø299.0 mm Monohole Expandable Casing

open access: yesShiyou jixie
In order to solve the problem of formation leakage in Shahejie Formation in Bohai Oilfield, it is necessary to develop expandable casings with large diameter, high compressive strength and good sealing performance to seal the cracks or faults in complex ...
Yang Baojian   +5 more
doaj   +1 more source

On Maskin monotonicity of solution based social choice rules [PDF]

open access: yes, 2007
Haake C-J, Trockel W. On Maskin monotonicity of solution based social choice rules. Working Papers. Institute of Mathematical Economics. Vol 393. Bielefeld: Universität Bielefeld; 2007.Howard (1992) argues that the Nash bargaining solution is not Nash ...
Haake, Claus-Jochen   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Computational Analysis of a Novel Iterative Scheme with an Application

open access: yesComputation
The computational study of fixed-point problems in distance spaces is an active and important research area. The purpose of this paper is to construct a new iterative scheme in the setting of Banach space for approximating solutions of fixed-point ...
Fayyaz Ahmad   +4 more
doaj   +1 more source

A Characterization of the average tree solution for tree games [PDF]

open access: yes
For the class of tree games, a new solution called the average tree solution has been proposed recently. We provide a characterization of this solution.
Dolf Talman, Debasis Mishra
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

ASSESSMENT OF INSECURITY IN SENIOR SCHOOLS IN IBI LOCAL GOVERNMENT AREA, TARABA STATE, NIGERIA

open access: yesSociological Education
One major problem affecting Nigeria today, which also bothers every dick, tom and harry is insecurity. Consequently, insecurity has taken various forms in different parts of the country, as there has been educational, social, and physical insecurity ...
Ifeoma Priscillilian Okafor   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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