Results 121 to 130 of about 12,904,011 (291)

Future Open Networks Cross-Domain Cognitive Orchestration: A Novel Design Paradigm

open access: yesIEEE Access
Future Open Networks (FONs) are envisioned as large-scale, decentralised, and data-driven systems designed with open interfaces and interoperable standards to deliver diverse services and applications.
Saptarshi Ghosh   +12 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Computational Analysis of a Novel Iterative Scheme with an Application

open access: yesComputation
The computational study of fixed-point problems in distance spaces is an active and important research area. The purpose of this paper is to construct a new iterative scheme in the setting of Banach space for approximating solutions of fixed-point ...
Fayyaz Ahmad   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

ASSESSMENT OF INSECURITY IN SENIOR SCHOOLS IN IBI LOCAL GOVERNMENT AREA, TARABA STATE, NIGERIA

open access: yesSociological Education
One major problem affecting Nigeria today, which also bothers every dick, tom and harry is insecurity. Consequently, insecurity has taken various forms in different parts of the country, as there has been educational, social, and physical insecurity ...
Ifeoma Priscillilian Okafor   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Quantum Painlev\'e II solution and Approximated analytic solution of the Yukawa Potential

open access: yes, 2014
We show that one dimensional non-stationary Schr\"odi-nger equation with a specific choice of potential reduces to the quantum Painlev\'e II equation and the solution of its Riccati form appears as a dominant term of that potential. Further, we show that
Mahmood, Irfan
core  

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