Results 31 to 40 of about 269,323 (268)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Results in Optics, 2021 Bis (2,6-Diaminopyridinium) single crystal hydrogen phthalate nitrate monohydrate (APPN) has been successfully cultivated via the growth method of slow evaporation solution. A single crystal X-ray diffraction analysis has confirmed the lattice parameters
P. Vivek +7 more
doaj +1 more source
Crystal growth in gelled solution: applications to coordination polymers
CrystEngComm, 2016 Some critical issues concerning the complex synthesis and crystallization of designed coordination polymers are highlighted by using gels as diffusion media. The systematic use of gel methods in a variety of different crystallization configurations has been proven useful in revealing the field of existence and the stability hierarchy of competitive and
S. Rizzato +4 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Restorative Dentistry & Endodontics, 2012 Objectives Present study was undertaken to investigate the crystal growth onto synthetic hydroxyapatite (HA) seeds in pH 4.3 and pH 7.0 supersaturated solutions with different fluoride concentrations. Materials and Methods 8 groups of pH 4.3 and 7.0
Haneol Shin +3 more
doaj +1 more source
Crystals, 2022 In this paper, an image measurement method using a high-speed imaging system is proposed for the evolution of crystal population sizes during cooling crystallization processes.
Yan Huo, Xin Li, Binbin Tu
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Scientific ReportsNon-photochemical laser-induced nucleation (NPLIN) in supersaturated potassium bromide (KBr) solutions with the addition of acidic polymers is reported here for the first time. Upon absorbing the incident laser, crystallites are immediately induced along
Shuai Li, Xiongfei Xie, Yao Liu
doaj +1 more source