Results 61 to 70 of about 266,750 (267)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of adding technologically processed antibodies to interferon-gamma into a parent solution on the structural features of triglycine sulfate crystals grown from this solution

Тонкие химические технологии
Objectives. Ferroelectric triglycine sulfate (TGS) belongs to a group of crystals whose properties are sensitive even to minor changes in growth conditions.
G. O. Stepanov, N. N. Rodionova, R. R. Konstantinov, K. A. Subbotin   +3 more
doaj   +1 more source

Modulating preferred crystal orientation for efficient and stable perovskite solar cells—From progress to perspectives

InfoMat, 2022
The perovskite solar cell (PSC) has been recognized as a promising candidate for the next generation of photovoltaics due to its excellent power conversion efficiency (PCE), potential low cost and straightforward solution preparation processes.
Zhimin Fang, Nan Yan, Shengzhong (Frank) Liu   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Encapsulation of nanoparticles into single-crystal ZnO nanorods and microrods

Beilstein Journal of Nanotechnology, 2014
One-dimensional single crystal incorporating functional nanoparticles of other materials could be an interesting platform for various applications. We studied the encapsulation of nanoparticles into single-crystal ZnO nanorods by exploiting the crystal ...
Jinzhang Liu, Marco Notarianni, Llew Rintoul, Nunzio Motta   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Suppression of the surface roughness by adjusting the temperature distribution in the top-seeded solution growth of SiC crystal

Journal of Materiomics
Spontaneous nucleation of SiC particles and giant macroscopic steps result in the surface roughness of the grown crystal for the top-seeded solution growth of SiC crystal. To suppress the surface roughness, the temperature gradient was carefully adjusted
Mengyu Li, Yuhui Liu, Xiaofang Qi, Wencheng Ma, Yongkuan Xu, Zhanggui Hu, Yicheng Wu   +6 more
doaj   +1 more source

Time-periodic solution for a fourth-order parabolic equation describing crystal surface growth

Electronic Journal of Qualitative Theory of Differential Equations, 2013
In this paper, by using the Galerkin method, the existence and uniqueness of time-periodic generalized solutions to a fourth-order parabolic equation describing crystal surface growth are proved.
Xiaopeng Zhao, Bo Liu, Ning Duan
doaj   +1 more source

Synthesis, growth, structural, optical and electrical properties of novel organic single crystal: p-toluidinium salicylate [PDF]

Modern Electronic Materials, 2018
A novel organic single crystal of p-toluidinium salicylate (PTSA) was grown by slow evaporation solution growth technique. The structure of grown crystal was determined from the single crystal X-ray diffraction analysis. The functional groups existing in
Shanmugam Suresh, M. Nizam Mohideen, G. Vinitha, R. Mohan Kumar   +3 more
doaj   +3 more sources