Results 71 to 80 of about 1,811,375 (268)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cidades, Comunidades e TerritórioThis essay aims to understand innovation in politics with the advent of the Internet from the 1990s onwards, emphasizing social movements that affect governments and States in partnerships with the market.
Marcelo Castañeda
doaj
Music-based Pedagogies to Teach Conversational Skills to Early Childhood Care and Education’s Learners:The Educators’ Constraints and the Proposed Solutions [PDF]
E-Journal of Humanities, Arts and Social SciencesThe indispensable requisite for sustainable, and equitable early childhood education is innovative educators with developmentally appropriate strategies to communicate essential skills to young children.
Deborah Avosuahi Arasomwan +1 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Sakarya University Journal of Education, 2013 The aim of this study is to explore the impact of conceptual change texts on the elimination of science teacher candidates misconceptions about the subject of solutions.
Deniz Altınışık +3 more
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Analysis of Effective Solutions in the Field of Waste Management in Municipalities [PDF]
International Journal of Agricultural Management and Development, 2017 The main purpose of this study was to analyze the effective solutions in the field of waste management in municipalities. The statistical population in this survey –based study consisted of the citizens that lived in Orumiyeh city in West Azerbaijan ...
Solieman Rasouliazar +1 more
doaj
In Praise of the No-Solution Solution
Journal of Political Sciences & Public Affairs, 2015 In order to enable systematic analyses of the numerous solutions to the Arab-Israeli conflict this study presents a model that maps them into a general typology along the continuum between the poles of Arab dominance over the country and Israeli dominance.
openaire +1 more source