Results 161 to 170 of about 23,096 (258)

Individual Differences in Learning and Cessation Predict Academic Performance. [PDF]

Behav Sci (Basel)
Macchione AL, Coldren J.
europepmc   +1 more source

Conditional sign-solvability

, 1992
Brualdi, Richard A.; Chavey, Keith L.; Shader, Bryan L.. (1992). Conditional sign-solvability.
Brualdi, Richard A., Chavey, Keith L., Shader, Bryan L.   +2 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Retrosynthetic crosstalk between single-step reaction and multi-step planning. [PDF]

J Cheminform
Choe J, Kim H, Chok YT, Gim M, Kang J.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

A multiscale theory for network advection- reaction-diffusion. [PDF]

J Math Biol
Oliveri H, Cozzolino E, Goriely A.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Entropic Confinement in String-Net Models: An Analogue Study via SU(2)_k Fusion Categories. [PDF]

Entropy (Basel)
Yang X.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Exploring Meta-Reasoning Propositional Confidence in Conspiratorial Beliefs and Socio-Cognitive Polarization. [PDF]

Open Mind (Camb)
Salvi C, Mielicki MK, Cancer A, Iannello P, George T.   +4 more
europepmc   +1 more source