Results 101 to 110 of about 2,765 (249)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Fractal and FractionalIn this article, we develop a compact finite difference scheme for a variable-order-time fractional-sub-diffusion equation of a fourth-order derivative term via order reduction.
Xin Zhang, Yu Bo, Yuanfeng Jin
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
First-order product-type systems of difference equations solvable in closed form
Electronic Journal of Differential Equations, 2015 We show that the first-order system of difference equations $$ z_{n+1}=\alpha z_n^aw_n^b,\quad w_{n+1}=\beta z_n^cw_n^d,\quad n\in\mathbb{N}_0, $$ where $a,b,c,d\in\mathbb{Z}$, $\alpha,\beta \in\mathbb{C}\setminus\{0\}$, $z_0, w_0\in\mathbb{C ...
Stevo Stevic
doaj
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
SOLVABILITY OF A FOUR DIMENSIONAL SYSTEM OF DIFFERENCE EQUATIONS
Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi B - Teorik BilimlerIn this study, we investigate the following four-dimensional difference equations system {█(u_n=(αu_(n-3) t_(n-2)+β)/(γv_(n-1) t_(n-2) u_(n-3) ), @v_n=(αv_(n-3) u_(n-2)+β)/(γw_(n-1) u_(n-2) v_(n-3) ),n∈N_0,@w_n=(αw_(n-3) v_(n-2)+β)/(γt_(n-1) v_(n-2) w_(n-3) ), @t_n=(αt_(n-3) w_(n-2)+β)/(γu_(n-1) w_(n-2) t_(n-3) ),
Şule DEVECİOĞLU, Merve KARA
openaire +2 more sources