Results 61 to 70 of about 2,673 (255)
Solvability of a Three-Dimensional System of Nonlinear Difference Equations
Mathematical Sciences and Applications E-Notes, 2022 In this paper, we solve the following three-dimensional system of difference equationsxn=yn−4zn−5yn−1(an+bnzn−2xn−3yn−4zn−5),yn=zn−4xn−5zn−1(αn+βnxn−2yn−3zn−4xn−5),zn=xn−4yn−5xn−1(An+Bnyn−2zn−3xn−4yn−5), n∈N0,xn=yn−4zn−5yn−1(an+bnzn−2xn−3yn−4zn−5),yn=zn−4xn−5zn−1(αn+βnxn−2yn−3zn−4xn−5),zn=xn−4yn−5xn−1(An+Bnyn−2zn−3xn−4yn−5), n∈N0,where the sequences ...
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Some functional-difference equations solvable in finitary functions [PDF]
St. Petersburg Mathematical Journal, 2007 The following equation \(q(-i\partial/\partial x)u(x)=(f\ast u)(Ax)\) is considered, where \(q\) is a polynomial with complex coefficients, \(f\) is a compactly supported distribution, and \(A:\mathbb{R}^n\to \mathbb{R}^n\) is a linear operator whose complexification has no spectrum in the closed unit disk. The author showed that the above equation has
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Electrical engineering & Electromechanics, 2016 Purpose. To elaborate a method of electric field numerical calculation in systems with curved boundaries between conductive and non-conductive mediums at final volume method usage and application of the rectangular grids. Methodology.
E.I. Sokol +3 more
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On some classes of solvable systems of difference equations [PDF]
Advances in Difference Equations, 2019 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Stevo Stević +3 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Solvability of boundary-value problems for a linear partial difference equation
Electronic Journal of Differential Equations, 2017 In this article we consider the two-dimensional boundary-value problem $$\displaylines{ d_{m,n}=d_{m-1,n}+f_nd_{m-1,n-1},\quad 1\le ...
Stevo Stevic
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