Results 131 to 140 of about 8,796 (305)
Determining a Group from Rational Tangles
, 2012 Color poster with text, charts, and formulas.The purpose of this study was to determine a subset from the set of rational tangles that will form a group.University of Wisconsin--Eau Claire Office of Research and Sponsored ...
Smith, Blake, Pang, Chao
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Bias of group generators in the solvable case
, 2015 Babai and Pak demonstrated a weakness in the product replacement algorithm, a widely used heuristic algorithm intended to rapidly generate nearly uniformly distributed random elements in a finite group G.
LUCCHINI, ANDREA +3 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Group rings with solvable 𝑛-Engel unit groups
, 1976 Let K G KG be the group ring of a group G G over a field of characteristic p ⩾ 0 , p ≠ 2 , 3 p \geqslant 0,\;p ...
M. M. Parmenter +2 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
ON THE BASE SIZE OF A TRANSITIVE GROUP WITH SOLVABLE POINT STABILIZER
, 2012 We prove that the base size of a transitive group G with solvable point stabilizer and with trivial solvable radical is not greater than k provided the same statement holds for the group of G-induced automorphisms of each nonabelian composition factor ...
E. P. VDOVIN
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source