Results 31 to 40 of about 5,622 (240)
Obeticholic Acid Forms Two Series of Isostructural Non-stoichiometric Channel Solvates
The aim of this work was to investigate solid forms of an active pharmaceutical substance, obeticholic acid, and to characterize the discovered structures. Obeticholic acid is used to treat primary biliary cholangitis.
Miloš Václavík (13205255) +6 more
core +1 more source
The Phenomenon of Self-Induced Diastereomeric Anisochrony and Its Implications in NMR Spectroscopy
Nuclear magnetic resonance (NMR) spectroscopy is an analytical technique largely applied in the analysis of discrimination processes involving enantiomeric substrates and chiral agents, which can interact with the analyte either via covalent bonding or ...
Federica Aiello +3 more
doaj +1 more source
Halogen and Hydrogen Bonding in Multicomponent Crystals of Tetrabromo-1H-Benzotriazole
4,5,6,7-Tetrabromo-1H-benzotriazole (TBBT) is still considered a reference inhibitor of casein kinase II (CK2), a valuable target for anticancer therapy, even though the poor solubility in water of this active pharmaceutical ingredient (API) has ...
Michele Baldrighi +4 more
doaj +1 more source
Reaction of Ni(NCS)2 with 3-methylpyridine in water leads to the formation of crystals of the title compound, [Ni(NCS)2(C6H7N)4]. All of them are of poor quality and non-merohedrally twinned but a refinement using data in HKLF-5 format leads to a ...
Christian Näther +2 more
doaj +1 more source
Solubility behaviour of CL-20 and HMX in organic solvents and solvates of CL-20
2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) and 1,3,5,7-tetranitro-1,3,5,7-tetrazoctane (HMX) are promising cocrystal coformers, but only little solubility data are available.
Dirk Herrmannsdörfer +2 more
doaj +1 more source
The study substantiates the importance of an objective quantitative assessment of the feasibility of creating innovative alliances (solvates) in the industry of the region as the basic platform for structural reform of the national economy especially in ...
L. G. Matveeva +3 more
doaj +1 more source
Background Atorvastatin calcium (ATC), an anti-lipid biopharmaceutical class II drug, is widely prescribed as a cholesterol-lowering agent and is presently the world’s best-selling medicine.
Chadha Renu +3 more
doaj +1 more source
Solvates of Ajmaline and Two-Dimensional Isostructurality between Methanol and Ethanol Solvates
Crystal structures of methanol, ethanol solvates, and two hydrates of ajmaline, acetonitrile solvate of ajmaline−isoajmaline cocrystal and one hydrate of ajmalinium bromide, are reported.
J. Sameena (2212969) +2 more
core +1 more source
On the Formation of Droperidol Solvates: Characterization of Structure and Properties
A solvate screening and characterization of the obtained solvates was performed to rationalize and understand the solvate formation of active pharamaceutical ingredient droperidol.
Agris Be̅rziņš (1605757) +3 more
core +2 more sources
Halogen-Bonding-Driven Self-Assembly of Solvates of Tetrabromoterephthalic Acid
Halogen bonding is one of the most interesting noncovalent attractions capable of self-assembly and recognition processes in both solution and solid phase.
Nucharee Chongboriboon +5 more
doaj +1 more source

