Results 31 to 40 of about 5,622 (240)

Obeticholic Acid Forms Two Series of Isostructural Non-stoichiometric Channel Solvates

open access: yes, 2022
The aim of this work was to investigate solid forms of an active pharmaceutical substance, obeticholic acid, and to characterize the discovered structures. Obeticholic acid is used to treat primary biliary cholangitis.
Miloš Václavík (13205255)   +6 more
core   +1 more source

The Phenomenon of Self-Induced Diastereomeric Anisochrony and Its Implications in NMR Spectroscopy

open access: yesMolecules, 2023
Nuclear magnetic resonance (NMR) spectroscopy is an analytical technique largely applied in the analysis of discrimination processes involving enantiomeric substrates and chiral agents, which can interact with the analyte either via covalent bonding or ...
Federica Aiello   +3 more
doaj   +1 more source

Halogen and Hydrogen Bonding in Multicomponent Crystals of Tetrabromo-1H-Benzotriazole

open access: yesCrystals, 2017
4,5,6,7-Tetrabromo-1H-benzotriazole (TBBT) is still considered a reference inhibitor of casein kinase II (CK2), a valuable target for anticancer therapy, even though the poor solubility in water of this active pharmaceutical ingredient (API) has ...
Michele Baldrighi   +4 more
doaj   +1 more source

Synthesis, crystal structure and thermal properties of tetrakis(3-methylpyridine-κN)bis(thiocyanato-κN)nickel(II)

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2023
Reaction of Ni(NCS)2 with 3-methylpyridine in water leads to the formation of crystals of the title compound, [Ni(NCS)2(C6H7N)4]. All of them are of poor quality and non-merohedrally twinned but a refinement using data in HKLF-5 format leads to a ...
Christian Näther   +2 more
doaj   +1 more source

Solubility behaviour of CL-20 and HMX in organic solvents and solvates of CL-20

open access: yesEnergetic Materials Frontiers, 2021
2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) and 1,3,5,7-tetranitro-1,3,5,7-tetrazoctane (HMX) are promising cocrystal coformers, but only little solubility data are available.
Dirk Herrmannsdörfer   +2 more
doaj   +1 more source

ECONOMIC AND MATHEMATICAL TOOLS FOR ASSESSING THE FEASIBILITY OF CREATING INDUSTRIAL INNOVATIVE SOLVATES

open access: yesНовые технологии, 2022
The study substantiates the importance of an objective quantitative assessment of the feasibility of creating innovative alliances (solvates) in the industry of the region as the basic platform for structural reform of the national economy especially in ...
L. G. Matveeva   +3 more
doaj   +1 more source

Characterisation and evaluation of pharmaceutical solvates of Atorvastatin calcium by thermoanalytical and spectroscopic studies

open access: yesChemistry Central Journal, 2012
Background Atorvastatin calcium (ATC), an anti-lipid biopharmaceutical class II drug, is widely prescribed as a cholesterol-lowering agent and is presently the world’s best-selling medicine.
Chadha Renu   +3 more
doaj   +1 more source

Solvates of Ajmaline and Two-Dimensional Isostructurality between Methanol and Ethanol Solvates

open access: yes, 2016
Crystal structures of methanol, ethanol solvates, and two hydrates of ajmaline, acetonitrile solvate of ajmaline−isoajmaline cocrystal and one hydrate of ajmalinium bromide, are reported.
J. Sameena (2212969)   +2 more
core   +1 more source

On the Formation of Droperidol Solvates: Characterization of Structure and Properties

open access: yes, 2016
A solvate screening and characterization of the obtained solvates was performed to rationalize and understand the solvate formation of active pharamaceutical ingredient droperidol.
Agris Be̅rziņš (1605757)   +3 more
core   +2 more sources

Halogen-Bonding-Driven Self-Assembly of Solvates of Tetrabromoterephthalic Acid

open access: yesCrystals, 2021
Halogen bonding is one of the most interesting noncovalent attractions capable of self-assembly and recognition processes in both solution and solid phase.
Nucharee Chongboriboon   +5 more
doaj   +1 more source

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