Results 51 to 60 of about 99,790 (313)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Solvation of Nanoscale Materials [PDF]

The utility of colloidal nanomaterials in energy storage devices, high-definition displays, and industrial coatings depends on their solution processibility and stability.
Carl, Brozek, Ashley, Mapile, Erik, Svensson Grape   +2 more
core   +1 more source

Machine Learning Guided Approach for Studying Solvation Environments [PDF]

, 2019
Toward practical modeling of local solvation effects of any solute in any solvent, we report a static and all-quantum mechanics based cluster-continuum approach for calculating single ion solvation free energies.
Ethan, Henderson, Susan, Rempe, Mitchell C., Groenenboom, Yasemin, Basdogan, Sandip, De, John, Keith   +5 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Using micro-solvation and generalized coordination numbers to estimate the solvation energies of adsorbed hydroxyl on metal nanoparticles [PDF]

, 2023
Solvent-adsorbate interactions have a great impact on catalytic processes in aqueous systems. Implicit solvent calculations are inexpensive but inaccurate toward hydrogen bonds, while a full incorporation of explicit solvation is computationally ...
Hanselman, S.R., Koper, M.T.M., Calle Vallejo, F., Federico Calle-Vallejo, Selwyn Hanselman, Marc T. M. Koper   +5 more
core   +1 more source

Effect of collagen-induced residual stress on the frictional property of articular cartilage

Biosurface and Biotribology, 2018
Previous findings, such as split-line of the articular cartilage surface and curving of sliced cartilage specimen, would suggest that residual stress is contained in articular cartilage.
Hiromichi Fujie, Sou Morishita, Seido Yarimitsu   +2 more
doaj   +1 more source

Anion Effects on the Liquid-Liquid Equilibrium Behavior of Pluronic L64 + Water + Sodium Salts at Different pH: Determination of Thermodynamic Parameters

Colloids and Interfaces, 2023
Two-phase aqueous systems have replaced and simplified steps in extraction and purification processes, especially for biocompounds. Thus, this study evaluated the liquid-liquid equilibrium behavior of Pluronic L64 + water + sodium salts at pH 5.0, 7.5 ...
Edson G. Monteiro-Junior, Josiel M. Costa, Otto A. Q. Jimenez, Bruno R. de Souza, Abimael C. Medeiros, Rodrigo C. Basso   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Minnesota Solvation Database (MNSOL) version 2012

, 2012
The Minnesota Solvation Database and User Manual is available for download as a .zip file named MNSolDatabase-v2012.The Minnesota Solvation Database consists of a collection of 3037 experimental free energies of solvation or transfer free energies for ...
Chambers, Candee C, Giesen, David J, Marenich, Aleksandr V, Kelly, Casey P, Cramer, Christopher J, Thompson, Jason D, Hawkins, Gregory D, Winget, Paul, Truhlar, Donald G   +8 more
core   +1 more source

Solvation Enthalpies and Free Energies for Organic Solvents through a Dense Neural Network: A Generalized-Born Approach

Liquids
A dense artificial neural network, ESE-ΔH-DNN, with two hidden layers for calculating both solvation free energies ΔG°solv and enthalpies ΔH°solv for neutral solutes in organic solvents is proposed.
Sergei F. Vyboishchikov
doaj   +1 more source