Results 71 to 80 of about 99,790 (313)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Anion solvation in alcohols [PDF]
, 1996 Anion solvation is measured in alcohols using pump-probe pulse radiolysis and the activation energy of solvation is determined. Solvation of an anion appears to be different than excited state solvation.
Jonah, C. D., Xujia, Zhang, Lin, Yi
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cation-Dependent Solvation Behavior of Aqueous Triflate Electrolytes [PDF]
We investigated trends in the cation-dependent solvation behavior and electrochemical stability of aqueous electrolytes with ten trifluoromethanesulfonate (OTf) salts (Li+, Na+, K+, NH4+, NMe3Et+, Mg2+, Zn2+, Ca2+, Ba2+, and Al3+). Our findings show that
Glenn, Pastel +4 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Is Passynski’s Approach to Hydration Numbers Consistent with Thermodynamics?
MoleculesHydrophilic and hydrophobic phenomena occur in aqueous solutions. Despite the complex nature of the molecular interactions, the propensity of molecules and ions to hydration is sometimes characterized by a single “hydration number”.
Wojciech Marczak
doaj +1 more source
Molecules, 2019 Monoclonal antibodies (mAbs) are often needed and applied in high concentration solutions, >100 mg/mL. Due to close intermolecular distances between mAbs at high concentrations (~10−20 nm at 200 mg/mL), intermolecular interactions between mAbs ...
Haleh H. Haeri +6 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Solvation pressure in chloroform
The Journal of Chemical Physics, 2006 Molecular dynamics (MD) simulations of chloroform vapor and liquid at normal temperature and pressure and liquid under hydrostatic pressure are presented, giving bond lengths and vibrational frequencies as functions of pressure. The change in bond lengths between vapor and liquid at normal temperature and pressure is consistent with a pressure ...
Hubel, H +3 more
openaire +5 more sources
Eplerenone ethanol solvate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 EPLERENONE [SYSTEMATIC NAME: 7α-(methoxy-carbon-yl)-3-oxo-9α,11-ep-oxy-17α-pregn-4-ene-21,17-carbolactone], an aldo-sterone receptor antagonist, crystallizes from ethanol as a monosolvate, C(24)H(30)O(6)·C(2)H(6)O. The eplerenone mol-ecule has two five-membered rings, three six-membered rings and one three-membered ring.
Duan-Jun Xu +4 more
openaire +3 more sources