Results 41 to 50 of about 110,089 (301)
Assessment of factors affecting the solvency of property-liability insurance companies
Journal of Innovations and SustainabilityPurpose. This study aims to determine the effect of company size, investment return ratio, own-retention ratio and underwriting results on both the solvency ratio based on technical provisions (YTP), and the solvency ratio based on net premiums (YNP) of ...
Houssem Krache +2 more
doaj +1 more source
Solvency I and Solvency II in Insurance Business [PDF]
Český finanční a účetní časopis, 2006 Zaklady projektu Solventnost II už byly položeny. Struktura je budovana na třech piliřich, obsahově srovnatelnými s Basel II. Přesto se vsak některými detaily mohou od sebe lisit. Těmito třemi piliři budou financni zdroje, řidici kontroly a tržni disciplina. Jeden z konceptu, který zcela jistě bude pro pojisťovny nový, bude orientace na kapital.
openaire +1 more source
Government solvency: revisiting some EMU countries [PDF]
, 2002 Corsetti and Roubini (1991) reported that the government finances of Greece, Ireland, Italy and the Netherlands did not satisfy the intertemporal budget constraint (IBC). We re-examine this issue by utilizing a new empirical approach and extended data
Arghyrou, MG, Luintel, KB
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Institutional investors in Germany : insurance companies and investment funds [PDF]
, 2003 This chapter focuses on institutional investors in the German financial markets. Institutional investors are specialized financial intermediaries who collect and manage funds on behalf of small investors toward specific objectives in terms of risk ...
Maurer, Raimond
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
MODELI OCJENE KREDITNOG BONITETA PREDUZEĆA [PDF]
Zbornik Radova Ekonomskog Fakulteta u Istočnom Sarajevu, 2014 The assessment of creditworthiness is based on a detailed analysis of financial reports of the company. The most common models of creditworthiness evaluation used by the companies are the traditional method, the Altman Z-score and Kralicek quicktest.
Zvjezdana Gavrilović, Borka Popović
doaj +1 more source
Generating VaR scenarios with product beta distributions [PDF]
, 2018 We propose a Monte Carlo simulation method to generate stress tests by VaR scenarios under Solvency II for dependent risks on the basis of observed data.
Pfeifer, Dietmar, Ragulina, Olena
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source