Results 51 to 60 of about 110,089 (301)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The impact of total capital on the financial stability and solvency of agricultural enterprises

Siberian Journal of Life Sciences and Agriculture
Background.  The study provides definitions of "capital", "total capital", "financial stability", "solvency", and analyzes the influence of the composition and structure of total capital on the financial stability and solvency of agricultural formations.
Innessa N. Efremenko, Oksana V. Butkova
doaj   +1 more source

Insurance Companies’ Solvency Management within de Framework of Logistic Capital Management Theory [PDF]

European Journal of Interdisciplinary Studies, 2011
Various models of economic growth, addressing the growth trends of country's economy, production, population and other structural objects are focused on the mathematical description of growth rates, taking into account the initial state of the object ...
Edita JURKONYTE
doaj  

Some Comments on QIS3. [PDF]

In this paper we discuss some issues proposed in the Solvency II - QIS3 report. In particular we comment and discuss the \AISAM-ACME study on non-life long tail liabilities; reserve risk and risk margin assessment under Solvency II".
Dhaene, Jan, Goovaerts, Marc, Van Weert, Koen   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Financial Performance with Asset Quality as Intervening Variable: Liquidity, Solvency and Operational Efficiency

Jurnal Ilmiah Bisnis dan Ekonomi Asia
Some banks in Indonesia that experience high solvency reflect an expansion strategy and aggressive lending. However, it also shows that there is a great risk in this large lending.
Selfi Hastria Ningsih, Aslan Hari Risetadi, Roza Gustika, Fitri Yeni   +3 more
doaj   +1 more source

DETERMINING THE RELATION BETWEEN THE BUSINESS ENVIRONMENT AND COMPANIES SOLVENCY FACTORS IN THE POST – CRISIS PERIOD

Ekonomika, 2017
In scientific literature, there aren’t clearly enough formulated reasons behind causing the solvency component elements changes that would help all companies to prepare for possible insolvency changes.
Deimena Kiyak, Linara Pranckevičiūtė
doaj   +1 more source

SOLVENCY INDICATOR IN THE CREDIT COOPERATIVES [PDF]

Solvency ratio is the best known indicator of banking prudence, with the priority to ensure the ability of credit institutions to meet the borrowers default and mitigate competitive inequalities between different national systems.caution, solvency, own ...
Csegedi Sándor, Popa Anamaria, Tiplea Augustin Liviu   +2 more
core