Results 71 to 80 of about 107,288 (354)
FEBS Open Bio, EarlyView.Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao +7 more
wiley +1 more source
Is regulating the solvency of banks counter-productive? [PDF]
This paper contains a critique of solvency regulation such as imposed on banks by Basel I and II. It argues that banks seeking to maximize rate of return on risk-adjusted capital (RORAC) aim at an optimal level of solvency because on the one hand ...
Dieter Pfaff +2 more
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FEBS Open Bio, EarlyView.Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti +8 more
wiley +1 more source
A market-consistent framework for the fair evaluation of insurance contracts under Solvency II [PDF]
, 2019 The entry into force of the Solvency II regulatory regime is pushing insurance companies in engaging into market consistence evaluation of their balance sheet, mainly with reference to financial options and guarantees embedded in life with-profit funds ...
Casalini, R. +3 more
core +2 more sources
Advanced Biology, EarlyView.Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers +3 more
wiley +1 more source
Вестник Северо-Кавказского федерального университетаIntroduction. In conditions of financial instability of an insurance company, which arises against the backdrop of problems of solvency, the management of the organization must introduce new methods of managing it.
V. P. Akinina, I. R. Temirbulatova
doaj +1 more source
Analysis of Georgia's Unemployment Insurance Trust Fund Reserves [PDF]
, 2006 This report analyses several aspects of Georgia's Unemployment Insurance Trust Fund, including the structure and the appropriate target level for the Trust Fund balance for the state of Georgia.
Edward Sennoga
core +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Factors Affecting Profitability in Indonesia's Retailing sub-sector (2019-2023)
AMAR (Andalas Management Review)This investigation seeks to examine the impact of liquidity and solvency on profitability in retailing sub-sector companies. Liquidity is gauged through the Current Ratio (CR) ratio while solvency uses Debt to Equity Ratio (DER). Profitability is gauged
Nurcika Putri +2 more
doaj +1 more source
Approaches to Formation of Technical Reserves of Insurance Organizations: Domestic Realities and International Requirements [PDF]
Problemi Ekonomiki, 2017 he aim of the article is to study approaches to formation of insurance reserves by insurance companies in Ukraine and the world. The essence and peculiarities of the formation of reserves by insurance organizations in Ukraine are investigated.
Prykaziuk Natalia V. +1 more
doaj